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Hemangiopericytoma/Solitary Fibrous Tumor of the Parietal Bone: A Case Report

Hemangiopericytoma/solitary fibrous tumor (HPC/STF) is a rare tumor arising from Zimmerman's pericytes and it is characterized by an aggressive malignancy, with a high tendency for local and distant recurrence. The authors report the case of a middle-aged woman with HPC/SFT of the right parieta...

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Autores principales: Neto, Ana Rita Dias, Leite, Regina, Rothwell, David, Roda, Domingos, Sousa, Claudia, Henriques, Mónica, Alves, Paula
Formato: Online Artículo Texto
Lenguaje:English
Publicado: S. Karger AG 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9830289/
https://www.ncbi.nlm.nih.gov/pubmed/36636675
http://dx.doi.org/10.1159/000525724
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author Neto, Ana Rita Dias
Leite, Regina
Rothwell, David
Roda, Domingos
Sousa, Claudia
Henriques, Mónica
Alves, Paula
author_facet Neto, Ana Rita Dias
Leite, Regina
Rothwell, David
Roda, Domingos
Sousa, Claudia
Henriques, Mónica
Alves, Paula
author_sort Neto, Ana Rita Dias
collection PubMed
description Hemangiopericytoma/solitary fibrous tumor (HPC/STF) is a rare tumor arising from Zimmerman's pericytes and it is characterized by an aggressive malignancy, with a high tendency for local and distant recurrence. The authors report the case of a middle-aged woman with HPC/SFT of the right parietal bone, which is an extremely rare primary location of involvement. The patient presented with a painful deformity of insidious growth at the right parietal region. Assessment with cranial computed tomography scan and magnetic resonance imaging revealed an expansive lesion at the right parietal bone, with exocranial extension and 27 mm of maximal diameter. Craniotomy with gross tumor removal, duraplasty, and cranioplasty was performed, and the diagnosis of HPC/SFT, WHO grade III, was established by pathological and immunohistochemical analysis. The patient was then evaluated for adjuvant radiation therapy and received a dose of 60 Gy (2 Gy/fraction) with 3D conformal radiotherapy to the surgical bed. The adjuvant treatment was uneventful and, after 8 months of follow-up, there was no suspected local or distant recurrence. The rarity of this diagnosis, its aggressive behavior, and the lack of published data posed several challenges for the treatment management.
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spelling pubmed-98302892023-01-11 Hemangiopericytoma/Solitary Fibrous Tumor of the Parietal Bone: A Case Report Neto, Ana Rita Dias Leite, Regina Rothwell, David Roda, Domingos Sousa, Claudia Henriques, Mónica Alves, Paula Case Rep Oncol Case Report Hemangiopericytoma/solitary fibrous tumor (HPC/STF) is a rare tumor arising from Zimmerman's pericytes and it is characterized by an aggressive malignancy, with a high tendency for local and distant recurrence. The authors report the case of a middle-aged woman with HPC/SFT of the right parietal bone, which is an extremely rare primary location of involvement. The patient presented with a painful deformity of insidious growth at the right parietal region. Assessment with cranial computed tomography scan and magnetic resonance imaging revealed an expansive lesion at the right parietal bone, with exocranial extension and 27 mm of maximal diameter. Craniotomy with gross tumor removal, duraplasty, and cranioplasty was performed, and the diagnosis of HPC/SFT, WHO grade III, was established by pathological and immunohistochemical analysis. The patient was then evaluated for adjuvant radiation therapy and received a dose of 60 Gy (2 Gy/fraction) with 3D conformal radiotherapy to the surgical bed. The adjuvant treatment was uneventful and, after 8 months of follow-up, there was no suspected local or distant recurrence. The rarity of this diagnosis, its aggressive behavior, and the lack of published data posed several challenges for the treatment management. S. Karger AG 2022-11-10 /pmc/articles/PMC9830289/ /pubmed/36636675 http://dx.doi.org/10.1159/000525724 Text en Copyright © 2022 by The Author(s). Published by S. Karger AG, Basel https://creativecommons.org/licenses/by-nc/4.0/This article is licensed under the Creative Commons Attribution-NonCommercial-4.0 International License (CC BY-NC) (http://www.karger.com/Services/OpenAccessLicense). Usage and distribution for commercial purposes requires written permission.
spellingShingle Case Report
Neto, Ana Rita Dias
Leite, Regina
Rothwell, David
Roda, Domingos
Sousa, Claudia
Henriques, Mónica
Alves, Paula
Hemangiopericytoma/Solitary Fibrous Tumor of the Parietal Bone: A Case Report
title Hemangiopericytoma/Solitary Fibrous Tumor of the Parietal Bone: A Case Report
title_full Hemangiopericytoma/Solitary Fibrous Tumor of the Parietal Bone: A Case Report
title_fullStr Hemangiopericytoma/Solitary Fibrous Tumor of the Parietal Bone: A Case Report
title_full_unstemmed Hemangiopericytoma/Solitary Fibrous Tumor of the Parietal Bone: A Case Report
title_short Hemangiopericytoma/Solitary Fibrous Tumor of the Parietal Bone: A Case Report
title_sort hemangiopericytoma/solitary fibrous tumor of the parietal bone: a case report
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9830289/
https://www.ncbi.nlm.nih.gov/pubmed/36636675
http://dx.doi.org/10.1159/000525724
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