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Impact of Hemin on Interleukin-21 Levels and Plasma Cells in Transfusion-Dependent Thalassemia with Positive and Negative Allo-Autoantibody

INTRODUCTION: Antibody formation in transfusion-dependent thalassemia is associated with chronic hemolysis and repeated transfusions. Hemolysis produces heme, which mediates B-cell differentiation into plasma cells and produces antibodies influenced by interleukin-21 (IL-21). OBJECTIVE: This study a...

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Detalles Bibliográficos
Autores principales:	Tambunan, Betty Agustina, Ugrasena, I Dewa Gede, Aryati, Aryati
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove 2023
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9830417/ https://www.ncbi.nlm.nih.gov/pubmed/36636711 http://dx.doi.org/10.2147/IJGM.S397317

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