Safety and Efficacy of Mek Inhibitors in the Treatment of Plexiform Neurofibromas: A Retrospective Study

INTRODUCTION: Plexiform neurofibromas (PN) represent the main cause of morbidity in patients affected by Neurofibromatosis Type 1 (NF1). Until recently, surgery has been the main treatment option in these patients, but it is burdened with a low efficacy rate and a high incidence of side effects as w...

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Detalles Bibliográficos
Autores principales: Cacchione, Antonella, Fabozzi, Francesco, Carai, Andrea, Colafati, Giovanna Stefania, del Baldo, Giada, Rossi, Sabrina, Diana, Martino, Megaro, Giacomina, Milano, Giuseppe Maria, Macchiaiolo, Marina, Crocoli, Alessandro, De Ioris, Maria Antonietta, Boccuto, Luigi, Secco, Domitilla Elena, Zama, Mario, Agolini, Emanuele, Tomà, Paolo, Mastronuzzi, Angela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2023
Materias:
Pediatric Precision Oncology: Target Therapy/New Drugs in Pediatric Brain Tumors-Original Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9830579/
https://www.ncbi.nlm.nih.gov/pubmed/36598023
http://dx.doi.org/10.1177/10732748221144930

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