Cargando…

Increasing the reflection efficiency of the Sedaconda ACD-S by heating and cooling the anaesthetic reflector: a bench study using a test lung

BACKGROUND: As volatile anaesthetic gases contribute to global warming, improving the efficiency of their delivery can reduce their environmental impact. This can be achieved by rebreathing from a circle system, but also by anaesthetic reflection with an open intensive care ventilator. We investigat...

Descripción completa

Detalles Bibliográficos
Autores principales: Meiser, Andreas, Meis, Pierre Louis Fernando, O’Gara, Brian, Volk, Thomas, Kermad, Azzeddine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9830614/
https://www.ncbi.nlm.nih.gov/pubmed/36625981
http://dx.doi.org/10.1007/s10877-022-00967-2
_version_ 1784867704612585472
author Meiser, Andreas
Meis, Pierre Louis Fernando
O’Gara, Brian
Volk, Thomas
Kermad, Azzeddine
author_facet Meiser, Andreas
Meis, Pierre Louis Fernando
O’Gara, Brian
Volk, Thomas
Kermad, Azzeddine
author_sort Meiser, Andreas
collection PubMed
description BACKGROUND: As volatile anaesthetic gases contribute to global warming, improving the efficiency of their delivery can reduce their environmental impact. This can be achieved by rebreathing from a circle system, but also by anaesthetic reflection with an open intensive care ventilator. We investigated whether the efficiency of such a reflection system could be increased by warming the reflector during inspiration and cooling it during expiration (thermocycling). METHODS: The Sedaconda-ACD-S (Sedana Medical, Danderyd, Sweden) was connected between an intensive care ventilator and a test lung. Liquid isoflurane was infused into the device at 0.5, 1.0, 2.0 and 5.0 mL/h; ventilator settings were 500 mL tidal volume, 12 bpm, 21% oxygen. Isoflurane concentrations were measured inside the test lung after equilibration. Thermocycling was achieved by heating the breathing gas in the inspiratory hose to 37 °C via a heated humidifier without water. Breathing gas expired from the test lung was cooled to 14 °C before reaching the ACD-S. In the test lung, body temperature pressure saturated conditions prevailed. Isoflurane concentrations and reflective efficiency were compared between thermocycling and control conditions. RESULTS: With thermocycling higher isoflurane concentrations in the test lung were measured for all infusion rates studied. Interpolation of data showed that for achieving 0.4 (0.6) Vol% isoflurane, the infusion rate can be reduced from 1.2 to 0.7 (2.0 to 1.2) mL/h or else to 56% (58%) of control. CONCLUSION: Thermocycling of the anaesthetic gas considerably increases the efficiency of the anaesthetic reflector and reduces anaesthetic consumption by almost half in a test lung model. Given that cooling can be miniaturized, this method carries a potential for further saving anaesthetics in clinical practice in the operating theatre as well as for inhaled sedation in the ICU.
format Online
Article
Text
id pubmed-9830614
institution National Center for Biotechnology Information
language English
publishDate 2023
publisher Springer Netherlands
record_format MEDLINE/PubMed
spelling pubmed-98306142023-01-10 Increasing the reflection efficiency of the Sedaconda ACD-S by heating and cooling the anaesthetic reflector: a bench study using a test lung Meiser, Andreas Meis, Pierre Louis Fernando O’Gara, Brian Volk, Thomas Kermad, Azzeddine J Clin Monit Comput Original Research BACKGROUND: As volatile anaesthetic gases contribute to global warming, improving the efficiency of their delivery can reduce their environmental impact. This can be achieved by rebreathing from a circle system, but also by anaesthetic reflection with an open intensive care ventilator. We investigated whether the efficiency of such a reflection system could be increased by warming the reflector during inspiration and cooling it during expiration (thermocycling). METHODS: The Sedaconda-ACD-S (Sedana Medical, Danderyd, Sweden) was connected between an intensive care ventilator and a test lung. Liquid isoflurane was infused into the device at 0.5, 1.0, 2.0 and 5.0 mL/h; ventilator settings were 500 mL tidal volume, 12 bpm, 21% oxygen. Isoflurane concentrations were measured inside the test lung after equilibration. Thermocycling was achieved by heating the breathing gas in the inspiratory hose to 37 °C via a heated humidifier without water. Breathing gas expired from the test lung was cooled to 14 °C before reaching the ACD-S. In the test lung, body temperature pressure saturated conditions prevailed. Isoflurane concentrations and reflective efficiency were compared between thermocycling and control conditions. RESULTS: With thermocycling higher isoflurane concentrations in the test lung were measured for all infusion rates studied. Interpolation of data showed that for achieving 0.4 (0.6) Vol% isoflurane, the infusion rate can be reduced from 1.2 to 0.7 (2.0 to 1.2) mL/h or else to 56% (58%) of control. CONCLUSION: Thermocycling of the anaesthetic gas considerably increases the efficiency of the anaesthetic reflector and reduces anaesthetic consumption by almost half in a test lung model. Given that cooling can be miniaturized, this method carries a potential for further saving anaesthetics in clinical practice in the operating theatre as well as for inhaled sedation in the ICU. Springer Netherlands 2023-01-10 2023 /pmc/articles/PMC9830614/ /pubmed/36625981 http://dx.doi.org/10.1007/s10877-022-00967-2 Text en © The Author(s) 2023 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Original Research
Meiser, Andreas
Meis, Pierre Louis Fernando
O’Gara, Brian
Volk, Thomas
Kermad, Azzeddine
Increasing the reflection efficiency of the Sedaconda ACD-S by heating and cooling the anaesthetic reflector: a bench study using a test lung
title Increasing the reflection efficiency of the Sedaconda ACD-S by heating and cooling the anaesthetic reflector: a bench study using a test lung
title_full Increasing the reflection efficiency of the Sedaconda ACD-S by heating and cooling the anaesthetic reflector: a bench study using a test lung
title_fullStr Increasing the reflection efficiency of the Sedaconda ACD-S by heating and cooling the anaesthetic reflector: a bench study using a test lung
title_full_unstemmed Increasing the reflection efficiency of the Sedaconda ACD-S by heating and cooling the anaesthetic reflector: a bench study using a test lung
title_short Increasing the reflection efficiency of the Sedaconda ACD-S by heating and cooling the anaesthetic reflector: a bench study using a test lung
title_sort increasing the reflection efficiency of the sedaconda acd-s by heating and cooling the anaesthetic reflector: a bench study using a test lung
topic Original Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9830614/
https://www.ncbi.nlm.nih.gov/pubmed/36625981
http://dx.doi.org/10.1007/s10877-022-00967-2
work_keys_str_mv AT meiserandreas increasingthereflectionefficiencyofthesedacondaacdsbyheatingandcoolingtheanaestheticreflectorabenchstudyusingatestlung
AT meispierrelouisfernando increasingthereflectionefficiencyofthesedacondaacdsbyheatingandcoolingtheanaestheticreflectorabenchstudyusingatestlung
AT ogarabrian increasingthereflectionefficiencyofthesedacondaacdsbyheatingandcoolingtheanaestheticreflectorabenchstudyusingatestlung
AT volkthomas increasingthereflectionefficiencyofthesedacondaacdsbyheatingandcoolingtheanaestheticreflectorabenchstudyusingatestlung
AT kermadazzeddine increasingthereflectionefficiencyofthesedacondaacdsbyheatingandcoolingtheanaestheticreflectorabenchstudyusingatestlung