Single-cell transcriptomics reveals a mechanosensitive injury signaling pathway in early diabetic nephropathy

BACKGROUND: Diabetic nephropathy (DN) is the leading cause of end-stage renal disease, and histopathologic glomerular lesions are among the earliest structural alterations of DN. However, the signaling pathways that initiate these glomerular alterations are incompletely understood. METHODS: To delin...

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Detalles Bibliográficos
Autores principales: Liu, Shuya, Zhao, Yu, Lu, Shun, Zhang, Tianran, Lindenmeyer, Maja T., Nair, Viji, Gies, Sydney E., Wu, Guochao, Nelson, Robert G., Czogalla, Jan, Aypek, Hande, Zielinski, Stephanie, Liao, Zhouning, Schaper, Melanie, Fermin, Damian, Cohen, Clemens D., Delic, Denis, Krebs, Christian F., Grahammer, Florian, Wiech, Thorsten, Kretzler, Matthias, Meyer-Schwesinger, Catherine, Bonn, Stefan, Huber, Tobias B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9830686/
https://www.ncbi.nlm.nih.gov/pubmed/36627643
http://dx.doi.org/10.1186/s13073-022-01145-4

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