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A two-stage genome-wide association study identifies novel germline genetic variations in CACNA2D3 associated with radiotherapy response in nasopharyngeal carcinoma

BACKGROUND: Radiotherapy (RT) is the standard treatment for nasopharyngeal carcinoma (NPC). However, due to individual differences in radiosensitivity, biomarkers are needed to tailored radiotherapy to cancer patients. However, comprehensive genome-wide radiogenomic studies on them are still lacking...

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Detalles Bibliográficos
Autores principales: Yu, Lu-Lu, Hu, Bi-Wen, Huang, Han-Xue, Yu, Bing, Xiao, Qi, Lv, Qiao-Li, Luo, Chen-Hui, Guo, Cheng-Xian, Li, Jin-Gao, Xie, Xiao-Xue, Yin, Ji-Ye
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9830790/
https://www.ncbi.nlm.nih.gov/pubmed/36624463
http://dx.doi.org/10.1186/s12967-022-03819-4

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