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Investigation of two metabolic engineering approaches for (R,R)-2,3-butanediol production from glycerol in Bacillus subtilis

BACKGROUND: Flux Balance Analysis (FBA) is a well-known bioinformatics tool for metabolic engineering design. Previously, we have successfully used single-level FBA to design metabolic fluxes in Bacillus subtilis to enhance (R,R)-2,3-butanediol (2,3-BD) production from glycerol. OptKnock is another...

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Detalles Bibliográficos
Autores principales: Vikromvarasiri, Nunthaphan, Noda, Shuhei, Shirai, Tomokazu, Kondo, Akihiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9830791/
https://www.ncbi.nlm.nih.gov/pubmed/36627686
http://dx.doi.org/10.1186/s13036-022-00320-w

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