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Investigation of two metabolic engineering approaches for (R,R)-2,3-butanediol production from glycerol in Bacillus subtilis
BACKGROUND: Flux Balance Analysis (FBA) is a well-known bioinformatics tool for metabolic engineering design. Previously, we have successfully used single-level FBA to design metabolic fluxes in Bacillus subtilis to enhance (R,R)-2,3-butanediol (2,3-BD) production from glycerol. OptKnock is another...
Autores principales: | Vikromvarasiri, Nunthaphan, Noda, Shuhei, Shirai, Tomokazu, Kondo, Akihiko |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9830791/ https://www.ncbi.nlm.nih.gov/pubmed/36627686 http://dx.doi.org/10.1186/s13036-022-00320-w |
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