Electric field stimulation boosts neuronal differentiation of neural stem cells for spinal cord injury treatment via PI3K/Akt/GSK-3β/β-catenin activation

BACKGROUND: Neural stem cells (NSCs) are considered as candidates for cell replacement therapy in many neurological disorders. However, the propensity for their differentiation to proceed more glial rather than neuronal phenotypes in pathological conditions limits positive outcomes of reparative tra...

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Detalles Bibliográficos
Autores principales: Liu, Qian, Telezhkin, Vsevolod, Jiang, Wenkai, Gu, Yu, Wang, Yan, Hong, Wei, Tian, Weiming, Yarova, Polina, Zhang, Gaofeng, Lee, Simon Ming-yuen, Zhang, Peng, Zhao, Min, Allen, Nicholas D., Hirsch, Emilio, Penninger, Josef, Song, Bing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9830810/
https://www.ncbi.nlm.nih.gov/pubmed/36624495
http://dx.doi.org/10.1186/s13578-023-00954-3

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