Cargando…

Exploration of the mechanism by which Huangqi Guizhi Wuwu decoction inhibits Lps-induced inflammation by regulating macrophage polarization based on network pharmacology

BACKGROUND: Huangqi Guizhi Wuwu decoction (HQGZWWD) is a traditional Chinese herbal medicine formulation with significant anti-inflammatory activity. However, its underlying mechanism remains unknown. Through network pharmacology and experimental validation, this study aimed to examine the potential...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wang, Sutong, Ji, Tianshu, Wang, Lin, Qu, Yiwei, Wang, Xinhui, Wang, Wenting, Lv, Mujie, Wang, Yongcheng, Li, Xiao, Jiang, Ping
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2023
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9830836/ https://www.ncbi.nlm.nih.gov/pubmed/36624435 http://dx.doi.org/10.1186/s12906-022-03826-4

Ejemplares similares

The mechanisms of Huangqi Guizhi Wuwu decoction in treating ischaemic stroke based on network pharmacology and experiment verification
por: Liao, Weiguo, et al.
Publicado: (2023)

Huangqi Guizhi Wuwu decoction in peripheral neurotoxicity treatment using network pharmacology and molecular docking
por: Chen, Tingting, et al.
Publicado: (2022)

An exploratory study on the mechanism of Huangqi Guizhi Wuwu Decoction in the treatment of neuropathic pain
por: Luo, Bo‐Yan, et al.
Publicado: (2022)

Huangqi Guizhi Wuwu decoction for diabetic peripheral neuropathy: Protocol for a systematic review
por: Zhang, Yuan, et al.
Publicado: (2019)

Huangqi Guizhi Wuwu Decoction Improves Arthritis and Pathological Damage of Heart and Lung in TNF-Tg Mice
por: Wang, Yi, et al.
Publicado: (2022)

Integrated network pharmacology and serum metabolomics approach deciphers the anti-colon cancer mechanisms of Huangqi Guizhi Wuwu Decoction
por: Pan, Boyu, et al.
Publicado: (2022)

HuangqiGuizhiWuwu Decoction Prevents Vascular Dysfunction in Diabetes via Inhibition of Endothelial Arginase 1
por: Cheng, Hong, et al.
Publicado: (2020)

The efficacy and safety of Huangqi Guizhi Wuwu decoction for rheumatoid arthritis: A protocol for systematic review and meta-analysis
por: Wang, Lei, et al.
Publicado: (2020)

Huangqi Guizhi Wuwu Decoction for treating cervical radiculopathy: A systematic review and meta-analysis of randomized controlled trials
por: Liang, Long, et al.
Publicado: (2020)

Erratum: HuangqiGuizhiWuwu Decoction Prevents Vascular Dysfunction in Diabetes via Inhibition of Endothelial Arginase 1
por: Frontiers Production Office,
Publicado: (2021)

Huangqi Guizhi Wuwu decoction alleviates oxaliplatin-induced peripheral neuropathy via the gut-peripheral nerve axis
por: Zhang, Zhengwei, et al.
Publicado: (2023)

Huangqi Guizhi Wuwu Decoction for treating diabetic peripheral neuropathy: a meta-analysis of 16 randomized controlled trials
por: Pang, Bing, et al.
Publicado: (2016)

Herbal formula Huangqi Guizhi Wuwu decoction attenuates paclitaxel-related neurotoxicity via inhibition of inflammation and oxidative stress
por: Lv, Zhangming, et al.
Publicado: (2021)

Effect and safety of Huangqi-Guizhi-Wuwu Decoction and Erxian Decoction in the treatment of frozen shoulder: A protocol for systematic review and meta-analysis
por: Zhang, You-Wei, et al.
Publicado: (2020)

Effectiveness of Huangqi Guizhi Wuwu decoction combined with rehabilitation training for shoulder hand syndrome after stroke: A systematic review and meta-analysis
por: Shi, Zhenyu, et al.
Publicado: (2023)

Pharmacokinetic Analysis of Huangqi Guizhi Wuwu Decoction on Blood and Brain Tissue in Rats with Normal and Cerebral Ischemia-Reperfusion Injury by Microdialysis with HPLC-MS/MS
por: Zheng, Hao-Zhen, et al.
Publicado: (2020)

Huangqi Guizhi Wuwu decoction promotes M2 microglia polarization and synaptic plasticity via Sirt1/NF-κB/NLRP3 pathway in MCAO rats
por: Ou, Zhijie, et al.
Publicado: (2023)

A Prospective, Randomized, Placebo-Controlled Study Assessing the Efficacy of Chinese Herbal Medicine (Huangqi Guizhi Wuwu Decoction) in the Treatment of Albumin-Bound Paclitaxel-Induced Peripheral Neuropathy
por: Chai, Yue, et al.
Publicado: (2023)

Huangqi Guizhi Wuwu Decoction can prevent and treat oxaliplatin-induced neuropathic pain by TNFα/IL-1β/IL-6/MAPK/NF-kB pathway
por: Li, Mingzhu, et al.
Publicado: (2022)

The therapeutic effect of modified Huangqi Guizhi Wuwu Tang for multiple myeloma: An 18-year follow-up case report
por: Tian, Mingmin, et al.
Publicado: (2017)

Identification of Active Ingredients of Huangqi Guizhi Wuwu Decoction for Promoting Nerve Function Recovery After Ischemic Stroke Using HT22 Live-Cell-Based Affinity Chromatography Combined with HPLC-MS/MS
por: He, Yingying, et al.
Publicado: (2021)

Mechanisms of Action of a Herbal Formula Huangqi Guizhi Wuwu Tang for the Management of Post-Stroke Related Numbness and Weakness: A Computational Molecular Docking Study
por: Lee, Sanghyun, et al.
Publicado: (2022)

Potential mechanisms of Guizhi decoction against hypertension based on network pharmacology and Dahl salt-sensitive rat model
por: Chen, Jiye, et al.
Publicado: (2021)

Network Pharmacology Analysis on the Mechanism of Huangqi Sijunzi Decoction in Treating Cancer-Related Fatigue
por: Cui, Yixin, et al.
Publicado: (2021)

Insights into the molecular mechanisms of Huangqi decoction on liver fibrosis via computational systems pharmacology approaches
por: Wang, Biting, et al.
Publicado: (2021)

Mechanism of Huangqi Sanxian Decoction Inhibiting Osteoclast Differentiation Based on Network Pharmacology
por: Shi, Jian-Xin, et al.
Publicado: (2022)

Huangqi-Danshen Decoction Ameliorates Adenine-Induced Chronic Kidney Disease by Modulating Mitochondrial Dynamics
por: Liu, Xinhui, et al.
Publicado: (2019)

Based on Network Pharmacology and Molecular Docking to Explore the Underlying Mechanism of Huangqi Gegen Decoction for Treating Diabetic Nephropathy
por: Ding, Shanshan, et al.
Publicado: (2021)

Network Pharmacology-Based Study of the Underlying Mechanisms of Huangqi Sijunzi Decoction for Alzheimer's Disease
por: Zhang, Wei, et al.
Publicado: (2021)

Molecular mechanisms of the Guizhi decoction on osteoarthritis based on an integrated network pharmacology and RNA sequencing approach with experimental validation
por: Chen, Yan, et al.
Publicado: (2023)

Study on the mechanism of Gualou Xiebai Guizhi decoction (GLXBGZD) in the treatment of coronary heart disease based on network pharmacology
por: Teng, Chao, et al.
Publicado: (2022)

Huangqi-Danshen decoction protects against cisplatin-induced acute kidney injury in mice
por: Liu, Xinhui, et al.
Publicado: (2023)

Network Pharmacology and In Vivo Analysis of Dahuang-Huangqi Decoction Effectiveness in Alleviating Renal Interstitial Fibrosis
por: Luo, Yan, et al.
Publicado: (2022)

Retracted: Network Pharmacology Analysis on the Mechanism of Huangqi Sijunzi Decoction in Treating Cancer-Related Fatigue
por: Healthcare Engineering, Journal of
Publicado: (2023)

Metabolomics Analysis Reveals the Protection Mechanism of Huangqi–Danshen Decoction on Adenine-Induced Chronic Kidney Disease in Rats
por: Liu, Xinhui, et al.
Publicado: (2019)

Network pharmacology analysis of molecular targets and related mechanisms of Guizhi decoction in treating of menopausal syndrome
por: Zhang, Qian, et al.
Publicado: (2022)

A multicenter, randomized, double-blind, placebo-controlled trial evaluating the efficacy and safety of Huangqi Guizhi Wuwutang granule in patients with rheumatoid arthritis
por: Wang, Yiru, et al.
Publicado: (2019)

Network Pharmacology and In Vivo Experimental Validation to Uncover the Renoprotective Mechanisms of Fangji Huangqi Decoction on Nephrotic Syndrome
por: Yin, Jiazhen, et al.
Publicado: (2022)

Network Pharmacology Study on Molecular Mechanisms of Zhishi Xiebai Guizhi Decoction in the Treatment of Coronary Heart Disease
por: Gao, Jin, et al.
Publicado: (2021)

Clinical efficacy evaluation and potential mechanism prediction on Guizhi-Shaoyao-Zhimu decoction in the treatment of gouty arthritis based on meta-analysis, network pharmacology analysis, and molecular docking
por: Qu, Pengda, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_2aeaqisffvrlre7plk9s1kevvd