Cargando…
Epidemiology and prevalence of pulmonary sequestration in Chinese population, 2010–2019
BACKGROUND: Pulmonary sequestration (PS) is the second common congenital lung malformation and has been known for over 150 years. However, there is a scarcity of epidemiological studies on it. This study aimed to characterize the epidemiology of pulmonary sequestration in Chinese population in the r...
Autores principales: | , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9830928/ https://www.ncbi.nlm.nih.gov/pubmed/36624419 http://dx.doi.org/10.1186/s12890-023-02308-8 |
_version_ | 1784867766383149056 |
---|---|
author | Gao, Yuyang Xu, Wenli Li, Wenyan Chen, Zhiyu Li, Qi Liu, Zhen Liu, Hanmin Dai, Li |
author_facet | Gao, Yuyang Xu, Wenli Li, Wenyan Chen, Zhiyu Li, Qi Liu, Zhen Liu, Hanmin Dai, Li |
author_sort | Gao, Yuyang |
collection | PubMed |
description | BACKGROUND: Pulmonary sequestration (PS) is the second common congenital lung malformation and has been known for over 150 years. However, there is a scarcity of epidemiological studies on it. This study aimed to characterize the epidemiology of pulmonary sequestration in Chinese population in the recent decade by using a nationwide database. METHODS: Using data from the Chinese Birth Defects Monitoring Network during 2010–2019, the prevalence rates for PS were calculated by birth year, maternal age, residence area, geographical region, and infant sex. Variations in prevalence and changes over time were further examined. Other variables of interest for analysis included the pregnancy outcomes of affected infants, the prenatal diagnosis, and the co-occurring anomalies of PS cases. RESULTS: During the study period, we identified an average prevalence rate of 0.31, 0.11, and 0.42 per 10,000 live and still births for the isolated, non-isolated, and overall PS, respectively. An upward trend was observed for each category of PS. The prevalence rates varied significantly by maternal age (< 20 years, 0.34/10,000; 20–24 years, 0.33/10,000; 25–29 years, 0.45/10,000; 30–34 years, 0.46/10,000; ≥ 35 years, 0.36/10,000), residence area (urban vs. rural, 0.51/10,000 vs. 0.30/10,000), geographical region (western, 0.33/10,000; eastern, 0.49/10,000; central, 0.43/10,000), and by infant sex (male vs. female, 0.45/10,000 vs. 0.38/10,000). Non-isolated PS cases were more likely born prematurely than isolated cases (15.29% vs. 7.83%). 40.28% and 33.80% of non-isolated cases were accompanied by additional respiratory, and circulatory system malformations, respectively. CONCLUSIONS: The study presents for the first time the prevalence of pulmonary sequestration in Chinese population. The rising prevalence and relatively poor perinatal outcome of affected fetuses or newborns indicate the necessity to improve perinatal management of PS. |
format | Online Article Text |
id | pubmed-9830928 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-98309282023-01-11 Epidemiology and prevalence of pulmonary sequestration in Chinese population, 2010–2019 Gao, Yuyang Xu, Wenli Li, Wenyan Chen, Zhiyu Li, Qi Liu, Zhen Liu, Hanmin Dai, Li BMC Pulm Med Research BACKGROUND: Pulmonary sequestration (PS) is the second common congenital lung malformation and has been known for over 150 years. However, there is a scarcity of epidemiological studies on it. This study aimed to characterize the epidemiology of pulmonary sequestration in Chinese population in the recent decade by using a nationwide database. METHODS: Using data from the Chinese Birth Defects Monitoring Network during 2010–2019, the prevalence rates for PS were calculated by birth year, maternal age, residence area, geographical region, and infant sex. Variations in prevalence and changes over time were further examined. Other variables of interest for analysis included the pregnancy outcomes of affected infants, the prenatal diagnosis, and the co-occurring anomalies of PS cases. RESULTS: During the study period, we identified an average prevalence rate of 0.31, 0.11, and 0.42 per 10,000 live and still births for the isolated, non-isolated, and overall PS, respectively. An upward trend was observed for each category of PS. The prevalence rates varied significantly by maternal age (< 20 years, 0.34/10,000; 20–24 years, 0.33/10,000; 25–29 years, 0.45/10,000; 30–34 years, 0.46/10,000; ≥ 35 years, 0.36/10,000), residence area (urban vs. rural, 0.51/10,000 vs. 0.30/10,000), geographical region (western, 0.33/10,000; eastern, 0.49/10,000; central, 0.43/10,000), and by infant sex (male vs. female, 0.45/10,000 vs. 0.38/10,000). Non-isolated PS cases were more likely born prematurely than isolated cases (15.29% vs. 7.83%). 40.28% and 33.80% of non-isolated cases were accompanied by additional respiratory, and circulatory system malformations, respectively. CONCLUSIONS: The study presents for the first time the prevalence of pulmonary sequestration in Chinese population. The rising prevalence and relatively poor perinatal outcome of affected fetuses or newborns indicate the necessity to improve perinatal management of PS. BioMed Central 2023-01-09 /pmc/articles/PMC9830928/ /pubmed/36624419 http://dx.doi.org/10.1186/s12890-023-02308-8 Text en © The Author(s) 2023 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated in a credit line to the data. |
spellingShingle | Research Gao, Yuyang Xu, Wenli Li, Wenyan Chen, Zhiyu Li, Qi Liu, Zhen Liu, Hanmin Dai, Li Epidemiology and prevalence of pulmonary sequestration in Chinese population, 2010–2019 |
title | Epidemiology and prevalence of pulmonary sequestration in Chinese population, 2010–2019 |
title_full | Epidemiology and prevalence of pulmonary sequestration in Chinese population, 2010–2019 |
title_fullStr | Epidemiology and prevalence of pulmonary sequestration in Chinese population, 2010–2019 |
title_full_unstemmed | Epidemiology and prevalence of pulmonary sequestration in Chinese population, 2010–2019 |
title_short | Epidemiology and prevalence of pulmonary sequestration in Chinese population, 2010–2019 |
title_sort | epidemiology and prevalence of pulmonary sequestration in chinese population, 2010–2019 |
topic | Research |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9830928/ https://www.ncbi.nlm.nih.gov/pubmed/36624419 http://dx.doi.org/10.1186/s12890-023-02308-8 |
work_keys_str_mv | AT gaoyuyang epidemiologyandprevalenceofpulmonarysequestrationinchinesepopulation20102019 AT xuwenli epidemiologyandprevalenceofpulmonarysequestrationinchinesepopulation20102019 AT liwenyan epidemiologyandprevalenceofpulmonarysequestrationinchinesepopulation20102019 AT chenzhiyu epidemiologyandprevalenceofpulmonarysequestrationinchinesepopulation20102019 AT liqi epidemiologyandprevalenceofpulmonarysequestrationinchinesepopulation20102019 AT liuzhen epidemiologyandprevalenceofpulmonarysequestrationinchinesepopulation20102019 AT liuhanmin epidemiologyandprevalenceofpulmonarysequestrationinchinesepopulation20102019 AT daili epidemiologyandprevalenceofpulmonarysequestrationinchinesepopulation20102019 |