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Pharmacological potentiators of the calcium signaling cascade identified by high-throughput screening

Pharmacological modulators of the Ca(2+) signaling cascade are important research tools and may translate into novel therapeutic strategies for a series of human diseases. We carried out a screening of a maximally diverse chemical library using the Ca(2+)-sensitive Cl(−) channel TMEM16A as a functio...

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Detalles Bibliográficos
Autores principales:	Genovese, Michele, Guidone, Daniela, Buccirossi, Martina, Borrelli, Anna, Rodriguez-Gimeno, Alejandra, Bertozzi, Fabio, Bandiera, Tiziano, Galietta, Luis J V
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2022
Materias:	Research Report
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9830948/ https://www.ncbi.nlm.nih.gov/pubmed/36712939 http://dx.doi.org/10.1093/pnasnexus/pgac288

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