Genetic Susceptibility to Chronic Kidney Disease: Links, Risks and Management

Chronic kidney disease (CKD) is associated with significant morbidity and mortality worldwide. In recent years, our understanding of genetic causes of CKD has expanded significantly with several renal conditions having been identified. This review discusses the current landscape of genetic kidney di...

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Autores principales: Sawaf, Hanny, Gudura, Tariku T, Dorobisz, Sylvester, Sandy, Dianne, Wang, Xiangling, Bobart, Shane A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2023
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9831004/
https://www.ncbi.nlm.nih.gov/pubmed/36636322
http://dx.doi.org/10.2147/IJNRD.S363041
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author Sawaf, Hanny
Gudura, Tariku T
Dorobisz, Sylvester
Sandy, Dianne
Wang, Xiangling
Bobart, Shane A
author_facet Sawaf, Hanny
Gudura, Tariku T
Dorobisz, Sylvester
Sandy, Dianne
Wang, Xiangling
Bobart, Shane A
author_sort Sawaf, Hanny
collection PubMed
description Chronic kidney disease (CKD) is associated with significant morbidity and mortality worldwide. In recent years, our understanding of genetic causes of CKD has expanded significantly with several renal conditions having been identified. This review discusses the current landscape of genetic kidney disease and their potential treatment options. This review will focus on cystic kidney disease, glomerular disease with genetic associations, congenital anomalies of kidneys and urinary tract (CAKUT), autosomal dominant-tubulointerstitial kidney disease (ADTKD), inherited nephrolithiasis and nephrocalcinosis.
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spelling pubmed-98310042023-01-11 Genetic Susceptibility to Chronic Kidney Disease: Links, Risks and Management Sawaf, Hanny Gudura, Tariku T Dorobisz, Sylvester Sandy, Dianne Wang, Xiangling Bobart, Shane A Int J Nephrol Renovasc Dis Review Chronic kidney disease (CKD) is associated with significant morbidity and mortality worldwide. In recent years, our understanding of genetic causes of CKD has expanded significantly with several renal conditions having been identified. This review discusses the current landscape of genetic kidney disease and their potential treatment options. This review will focus on cystic kidney disease, glomerular disease with genetic associations, congenital anomalies of kidneys and urinary tract (CAKUT), autosomal dominant-tubulointerstitial kidney disease (ADTKD), inherited nephrolithiasis and nephrocalcinosis. Dove 2023-01-05 /pmc/articles/PMC9831004/ /pubmed/36636322 http://dx.doi.org/10.2147/IJNRD.S363041 Text en © 2023 Sawaf et al. https://creativecommons.org/licenses/by-nc/3.0/This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution – Non Commercial (unported, v3.0) License (http://creativecommons.org/licenses/by-nc/3.0/ (https://creativecommons.org/licenses/by-nc/3.0/) ). By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms (https://www.dovepress.com/terms.php).
spellingShingle Review
Sawaf, Hanny
Gudura, Tariku T
Dorobisz, Sylvester
Sandy, Dianne
Wang, Xiangling
Bobart, Shane A
Genetic Susceptibility to Chronic Kidney Disease: Links, Risks and Management
title Genetic Susceptibility to Chronic Kidney Disease: Links, Risks and Management
title_full Genetic Susceptibility to Chronic Kidney Disease: Links, Risks and Management
title_fullStr Genetic Susceptibility to Chronic Kidney Disease: Links, Risks and Management
title_full_unstemmed Genetic Susceptibility to Chronic Kidney Disease: Links, Risks and Management
title_short Genetic Susceptibility to Chronic Kidney Disease: Links, Risks and Management
title_sort genetic susceptibility to chronic kidney disease: links, risks and management
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9831004/
https://www.ncbi.nlm.nih.gov/pubmed/36636322
http://dx.doi.org/10.2147/IJNRD.S363041
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