Sequence-Defined Heteromultivalent Precision Glycomacromolecules Bearing Sulfonated/Sulfated Nonglycosidic Moieties Preferentially Bind Galectin-3 and Delay Wound Healing of a Galectin-3 Positive Tumor Cell Line in an In Vitro Wound Scratch Assay

Within this work, a new class of sequence-defined heteromultivalent glycomacromolecules bearing lactose residues and nonglycosidic motifs for probing glycoconjugate recognition in carbohydrate recognition domain (CRD) of galectin-3 is presented. Galectins, a family of β-galactoside-binding proteins,...

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Detalles Bibliográficos
Autores principales: Freichel, Tanja, Heine, Viktoria, Laaf, Dominic, Mackintosh, Eleanor E., Sarafova, Sophia, Elling, Lothar, Snyder, Nicole L., Hartmann, Laura
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9831253/
https://www.ncbi.nlm.nih.gov/pubmed/32715650
http://dx.doi.org/10.1002/mabi.202000163

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