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Neonatal ketamine exposure impairs infrapyramidal bundle pruning and causes lasting increase in excitatory synaptic transmission in hippocampal CA3 neurons

Preclinical models demonstrate that nearly all anesthetics cause widespread neuroapoptosis in the developing brains of infant rodents and non-human primates. Anesthesia-induced developmental apoptosis is succeeded by prolonged neuropathology in the surviving neurons and lasting cognitive impairments...

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Detalles Bibliográficos
Autores principales:	Cabrera, Omar Hoseá, Useinovic, Nemanja, Maksimovic, Stefan, Near, Michelle, Quillinan, Nidia, Todorovic, Slobodan M., Jevtovic-Todorovic, Vesna
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9831613/ https://www.ncbi.nlm.nih.gov/pubmed/36371060 http://dx.doi.org/10.1016/j.nbd.2022.105923

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