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EMERGENCY SURGERY FOR OBSTRUCTING COLON CANCER: MORBIDITY AND RISK FACTORS OF EARLY POSTOPERATIVE MORTALITY – A COHORT STUDY OF 118 CASES

BACKGROUND: Occlusion is the most common complication of colon cancer. Surgical treatment is associated with the highest morbidity and mortality rate (10–27%) and has the worst prognosis. It is necessary for immediate management, avoiding colic perforation and peritonitis. The increase in mortality...

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Autores principales: ZAAFOURI, Haithem, CHERIF, Mona, KHEDHIRI, Nizar, MESBAHI, Meryam, ZEBDA, Helmo, JOUINI, Raja, BELLALI, Hedia, BEN MAAMER, Anis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Colégio Brasileiro de Cirurgia Digestiva 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9831636/
https://www.ncbi.nlm.nih.gov/pubmed/36629687
http://dx.doi.org/10.1590/0102-672020220002e1706
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author ZAAFOURI, Haithem
CHERIF, Mona
KHEDHIRI, Nizar
MESBAHI, Meryam
ZEBDA, Helmo
JOUINI, Raja
BELLALI, Hedia
BEN MAAMER, Anis
author_facet ZAAFOURI, Haithem
CHERIF, Mona
KHEDHIRI, Nizar
MESBAHI, Meryam
ZEBDA, Helmo
JOUINI, Raja
BELLALI, Hedia
BEN MAAMER, Anis
author_sort ZAAFOURI, Haithem
collection PubMed
description BACKGROUND: Occlusion is the most common complication of colon cancer. Surgical treatment is associated with the highest morbidity and mortality rate (10–27%) and has the worst prognosis. It is necessary for immediate management, avoiding colic perforation and peritonitis. The increase in mortality in emergency colon cancer surgery is multifactorial. AIMS: The aim of this study was to identify the risk factors for early postoperative mortality that highlights the therapeutic strategy in the management of obstructive colon cancer. METHODS: A retrospective study was performed on patients admitted from 2008 to 2020 at the Department of General Surgery due to obstructive colon cancer and operated on as an emergency (within 24 h of admission). RESULTS: In all, 118 patients with colon cancer were operated, and the early postoperative mortality was 10.2%. The univariate analysis highlighted that the American Society of Anesthesiology score III or IV, perforation tumor, one postoperative complication, and two simultaneous postoperative complications were considered significant risk factors for early postoperative mortality after emergent surgery. Multivariate analysis showed that only tumor perforation and the occurrence of two postoperative complications were significant risk factors. CONCLUSION: This study showed that postoperative complication is the leading cause of early postoperative mortality after emergency surgery for obstructive colon cancer. Optimizing the postoperative management of these higher risk patients is still necessary and may reduce the mortality rate.
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spelling pubmed-98316362023-01-18 EMERGENCY SURGERY FOR OBSTRUCTING COLON CANCER: MORBIDITY AND RISK FACTORS OF EARLY POSTOPERATIVE MORTALITY – A COHORT STUDY OF 118 CASES ZAAFOURI, Haithem CHERIF, Mona KHEDHIRI, Nizar MESBAHI, Meryam ZEBDA, Helmo JOUINI, Raja BELLALI, Hedia BEN MAAMER, Anis Arq Bras Cir Dig Original Article BACKGROUND: Occlusion is the most common complication of colon cancer. Surgical treatment is associated with the highest morbidity and mortality rate (10–27%) and has the worst prognosis. It is necessary for immediate management, avoiding colic perforation and peritonitis. The increase in mortality in emergency colon cancer surgery is multifactorial. AIMS: The aim of this study was to identify the risk factors for early postoperative mortality that highlights the therapeutic strategy in the management of obstructive colon cancer. METHODS: A retrospective study was performed on patients admitted from 2008 to 2020 at the Department of General Surgery due to obstructive colon cancer and operated on as an emergency (within 24 h of admission). RESULTS: In all, 118 patients with colon cancer were operated, and the early postoperative mortality was 10.2%. The univariate analysis highlighted that the American Society of Anesthesiology score III or IV, perforation tumor, one postoperative complication, and two simultaneous postoperative complications were considered significant risk factors for early postoperative mortality after emergent surgery. Multivariate analysis showed that only tumor perforation and the occurrence of two postoperative complications were significant risk factors. CONCLUSION: This study showed that postoperative complication is the leading cause of early postoperative mortality after emergency surgery for obstructive colon cancer. Optimizing the postoperative management of these higher risk patients is still necessary and may reduce the mortality rate. Colégio Brasileiro de Cirurgia Digestiva 2023-01-09 /pmc/articles/PMC9831636/ /pubmed/36629687 http://dx.doi.org/10.1590/0102-672020220002e1706 Text en https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License
spellingShingle Original Article
ZAAFOURI, Haithem
CHERIF, Mona
KHEDHIRI, Nizar
MESBAHI, Meryam
ZEBDA, Helmo
JOUINI, Raja
BELLALI, Hedia
BEN MAAMER, Anis
EMERGENCY SURGERY FOR OBSTRUCTING COLON CANCER: MORBIDITY AND RISK FACTORS OF EARLY POSTOPERATIVE MORTALITY – A COHORT STUDY OF 118 CASES
title EMERGENCY SURGERY FOR OBSTRUCTING COLON CANCER: MORBIDITY AND RISK FACTORS OF EARLY POSTOPERATIVE MORTALITY – A COHORT STUDY OF 118 CASES
title_full EMERGENCY SURGERY FOR OBSTRUCTING COLON CANCER: MORBIDITY AND RISK FACTORS OF EARLY POSTOPERATIVE MORTALITY – A COHORT STUDY OF 118 CASES
title_fullStr EMERGENCY SURGERY FOR OBSTRUCTING COLON CANCER: MORBIDITY AND RISK FACTORS OF EARLY POSTOPERATIVE MORTALITY – A COHORT STUDY OF 118 CASES
title_full_unstemmed EMERGENCY SURGERY FOR OBSTRUCTING COLON CANCER: MORBIDITY AND RISK FACTORS OF EARLY POSTOPERATIVE MORTALITY – A COHORT STUDY OF 118 CASES
title_short EMERGENCY SURGERY FOR OBSTRUCTING COLON CANCER: MORBIDITY AND RISK FACTORS OF EARLY POSTOPERATIVE MORTALITY – A COHORT STUDY OF 118 CASES
title_sort emergency surgery for obstructing colon cancer: morbidity and risk factors of early postoperative mortality – a cohort study of 118 cases
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9831636/
https://www.ncbi.nlm.nih.gov/pubmed/36629687
http://dx.doi.org/10.1590/0102-672020220002e1706
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