Case report: Challenges in immune reconstitution following hematopoietic stem cell transplantation for CTLA-4 insufficiency-like primary immune regulatory disorders

Cytotoxic T-lymphocyte antigen-4 (CTLA-4) haploinsufficiency is a T-cell hyperactivation disorder that can manifest with both immunodeficiency and immune dysregulation. Approximately one-third of patients may present mild symptoms and remain stable under supportive care. The remaining patients may d...

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Detalles Bibliográficos
Autores principales: Margarit-Soler, Adriana, Deyà-Martínez, Àngela, Canizales, Juan Torres, Vlagea, Alexandru, García-García, Ana, Marsal, Júlia, Del Castillo, Maria Trabazo, Planas, Sílvia, Simó, Sílvia, Esteve-Sole, Ana, Grande, María Suárez-Lledó, Badell, Isabel, Tarrats, Montserrat Rovira, Fernández-Avilés, Francesc, Alsina, Laia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9831655/
https://www.ncbi.nlm.nih.gov/pubmed/36636328
http://dx.doi.org/10.3389/fimmu.2022.1070068

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