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Role of m6A modification and novel circ_0066715/ miR-486-5p/ ETS1 axis in rheumatoid arthritis macrophage polarization progression

Rheumatoid arthritis (RA) is a systemic disease dominated by inflammatory synovitis. RA synovial macrophages tend undergo M1-type macrophage polarization. Then, polarized M1-type macrophages secrete abundant pro-inflammatory cytokines, causing joint and cartilage destruction. N6-methyladenosine (m6A...

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Detalles Bibliográficos
Autores principales:	Wan, Lei, Liu, Jian, Huang, Chuanbing, Zhu, Ziheng, Li, Fangze, Sun, Guanghan, Wang, Kun, Li, Shu, Ma, Ximeng, Chen, Xi, Yuan, Wang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals 2022
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9831719/ https://www.ncbi.nlm.nih.gov/pubmed/36541909 http://dx.doi.org/10.18632/aging.204439

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