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Associations of the APOE ε2 and ε4 alleles and polygenic profiles comprising APOE-TOMM40-APOC1 variants with Alzheimer’s disease biomarkers

Capturing the genetic architecture of Alzheimer’s disease (AD) is challenging because of the complex interplay of genetic and non-genetic factors in its etiology. It has been suggested that AD biomarkers may improve the characterization of AD pathology and its genetic architecture. Most studies have...

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Detalles Bibliográficos
Autores principales: Kulminski, Alexander M., Jain-Washburn, Ethan, Loiko, Elena, Loika, Yury, Feng, Fan, Culminskaya, Irina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9831745/
https://www.ncbi.nlm.nih.gov/pubmed/36399096
http://dx.doi.org/10.18632/aging.204384

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