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Associations of the APOE ε2 and ε4 alleles and polygenic profiles comprising APOE-TOMM40-APOC1 variants with Alzheimer’s disease biomarkers
Capturing the genetic architecture of Alzheimer’s disease (AD) is challenging because of the complex interplay of genetic and non-genetic factors in its etiology. It has been suggested that AD biomarkers may improve the characterization of AD pathology and its genetic architecture. Most studies have...
Autores principales: | Kulminski, Alexander M., Jain-Washburn, Ethan, Loiko, Elena, Loika, Yury, Feng, Fan, Culminskaya, Irina |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9831745/ https://www.ncbi.nlm.nih.gov/pubmed/36399096 http://dx.doi.org/10.18632/aging.204384 |
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