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Safety and Tolerability of Nicotinamide Riboside in Heart Failure With Reduced Ejection Fraction

The mitochondrial dysfunction characteristic of heart failure (HF) is associated with changes in intracellular nicotinamide adenine dinucleotide (NAD(+)) and NADH levels. Raising NAD(+) levels with the NAD(+) precursor, nicotinamide riboside (NR), may represent a novel HF treatment. In this 30-parti...

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Detalles Bibliográficos
Autores principales:	Wang, Dennis D., Airhart, Sophia E., Zhou, Bo, Shireman, Laura M., Jiang, Siyi, Melendez Rodriguez, Carolina, Kirkpatrick, James N., Shen, Danny D., Tian, Rong, O’Brien, Kevin D.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2022
Materias:	Original Research - Clinical
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9831861/ https://www.ncbi.nlm.nih.gov/pubmed/36644285 http://dx.doi.org/10.1016/j.jacbts.2022.06.012

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