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PLK1 and AURKB phosphorylate survivin differentially to affect proliferation in racially distinct triple-negative breast cancer

Protein diversity due to alternative mRNA splicing or post-translational modifications (PTMs) plays a vital role in various cellular functions. The mitotic kinases polo-like kinase 1 (PLK1) and Aurora B (AURKB) phosphorylate survivin, an inhibitor of apoptosis (IAP) family member, thereby regulating...

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Detalles Bibliográficos
Autores principales: Garlapati, Chakravarthy, Joshi, Shriya, Bhattarai, Shristi, Krishnamurthy, Jayashree, Turaga, Ravi Chakra, Nguyen, Thi, Li, Xiaoxian, Aneja, Ritu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9832024/
https://www.ncbi.nlm.nih.gov/pubmed/36627281
http://dx.doi.org/10.1038/s41419-022-05539-5