Cargando…

PLK1 and AURKB phosphorylate survivin differentially to affect proliferation in racially distinct triple-negative breast cancer

Protein diversity due to alternative mRNA splicing or post-translational modifications (PTMs) plays a vital role in various cellular functions. The mitotic kinases polo-like kinase 1 (PLK1) and Aurora B (AURKB) phosphorylate survivin, an inhibitor of apoptosis (IAP) family member, thereby regulating...

Descripción completa

Detalles Bibliográficos
Autores principales:	Garlapati, Chakravarthy, Joshi, Shriya, Bhattarai, Shristi, Krishnamurthy, Jayashree, Turaga, Ravi Chakra, Nguyen, Thi, Li, Xiaoxian, Aneja, Ritu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9832024/ https://www.ncbi.nlm.nih.gov/pubmed/36627281 http://dx.doi.org/10.1038/s41419-022-05539-5

Ejemplares similares

Epigenetic Determinants of Racial Disparity in Breast Cancer: Looking beyond Genetic Alterations
por: Joshi, Shriya, et al.
Publicado: (2022)

Monoethanolamine-induced glucose deprivation promotes apoptosis through metabolic rewiring in prostate cancer
por: Garlapati, Chakravarthy, et al.
Publicado: (2021)

Exosomal Metabolic Signatures Are Associated with Differential Response to Neoadjuvant Chemotherapy in Patients with Breast Cancer
por: Joshi, Shriya, et al.
Publicado: (2022)

Multi-institutional study of nuclear KIFC1 as a biomarker of poor prognosis in African American women with triple-negative breast cancer
por: Ogden, Angela, et al.
Publicado: (2017)

Digital image analysis and machine learning-assisted prediction of neoadjuvant chemotherapy response in triple-negative breast cancer
por: Fisher, Timothy B., et al.
Publicado: (2023)

Prevalence and Mortality of Triple-Negative Breast Cancer in West Africa: Biologic and Sociocultural Factors
por: Nwagu, Gift C., et al.
Publicado: (2021)

Quadruple-negative breast cancer: novel implications for a new disease
por: Bhattarai, Shristi, et al.
Publicado: (2020)

Quadruple-Negative Breast Cancer: An Uneven Playing Field
por: Saini, Geetanjali, et al.
Publicado: (2020)

Monitoring the dynamics of hemeoxygenase-1 activation in head and neck cancer cells in real-time using plasmonically enhanced Raman spectroscopy
por: Panikkanvalappil, Sajanlal R., et al.
Publicado: (2019)

Liaisons between Survivin and Plk1 during Cell Division and Cell Death
por: Colnaghi, Rita, et al.
Publicado: (2010)

AURKB as a Promising Prognostic Biomarker in Hepatocellular Carcinoma
por: Xiao, Jingchuan, et al.
Publicado: (2021)

Polymorphisms in AURKA and AURKB are associated with the survival of triple-negative breast cancer patients treated with taxane-based adjuvant chemotherapy
por: Liao, Yuqian, et al.
Publicado: (2018)

SARS-CoV-2 Infection in Cancer Patients: Effects on Disease Outcomes and Patient Prognosis
por: Seth, Gaurav, et al.
Publicado: (2020)

AURKB Promotes the Metastasis of Gastric Cancer, Possibly by Inducing EMT
por: Wang, Zhen, et al.
Publicado: (2020)

Spatial Separation of Plk1 Phosphorylation and Activity
por: Bruinsma, Wytse, et al.
Publicado: (2015)

Combined HER3-EGFR score in triple-negative breast cancer provides prognostic and predictive significance superior to individual biomarkers
por: Ogden, Angela, et al.
Publicado: (2020)

VRK1 and AURKB form a complex that cross inhibit their kinase activity and the phosphorylation of histone H3 in the progression of mitosis
por: Moura, David S., et al.
Publicado: (2018)

AURKB: a promising biomarker in clear cell renal cell carcinoma
por: Wan, Bangbei, et al.
Publicado: (2019)

Phosphorylation of PLK3 Is Controlled by Protein Phosphatase 6
por: Aquino Perez, Cecilia, et al.
Publicado: (2020)

QNBC Is Associated with High Genomic Instability Characterized by Copy Number Alterations and miRNA Deregulation
por: Bhattarai, Shristi, et al.
Publicado: (2021)

Protein Conformational Changes in Breast Cancer Sera Using Infrared Spectroscopic Analysis
por: Ghimire, Hemendra, et al.
Publicado: (2020)

EM011 activates a survivin-dependent apoptotic program in human non-small cell lung cancer cells
por: Karna, Prasanthi, et al.
Publicado: (2009)

Phosphorylation Modulates Survivin Function in Behcet’s Disease
por: Pahlavan, Yasamin, et al.
Publicado: (2020)

Deep learning based registration of serial whole-slide histopathology images in different stains
por: Roy, Mousumi, et al.
Publicado: (2023)

Haspin inhibition reveals functional differences of interchromatid axis–localized AURKB and AURKC
por: Quartuccio, Suzanne M., et al.
Publicado: (2017)

AURKB promotes gastric cancer progression via activation of CCND1 expression
por: Nie, Min, et al.
Publicado: (2020)

MYC degradation via AURKB inhibition: a new brake in the path to T-ALL
por: Zhang, Wu, et al.
Publicado: (2020)

AURKB Enhances Chromosomal Remodeling of Telomeric Genes and Accelerates Tumorigenesis of Uveal Melanoma
por: Wang, Huixue, et al.
Publicado: (2023)

Phosphorylation by Cdk1 induces Plk1-mediated vimentin phosphorylation during mitosis
por: Yamaguchi, Tomoya, et al.
Publicado: (2005)

Plk4-dependent phosphorylation of STIL is required for centriole duplication
por: Kratz, Anne-Sophie, et al.
Publicado: (2015)

PLK1 phosphorylation of pericentrin initiates centrosome maturation at the onset of mitosis
por: Lee, Kwanwoo, et al.
Publicado: (2011)

PLK1 Interacts and Phosphorylates Axin That Is Essential for Proper Centrosome Formation
por: Ruan, Ka, et al.
Publicado: (2012)

Proper chromosome alignment depends on BRCA2 phosphorylation by PLK1
por: Ehlén, Åsa, et al.
Publicado: (2020)

PLK1 Regulates MicroRNA Biogenesis through Drosha Phosphorylation
por: Fletcher, Claire Emily, et al.
Publicado: (2023)

Associations between health insurance status, neighborhood deprivation, and treatment delays in women with breast cancer living in Georgia
por: Awan, Sofia, et al.
Publicado: (2023)

Tumor Suppressor PLK2 May Serve as a Biomarker in Triple-Negative Breast Cancer for Improved Response to PLK1 Therapeutics
por: Gao, Yang, et al.
Publicado: (2021)

Distinctions in Breast Tumor Recurrence Patterns Post-Therapy among Racially Distinct Populations
por: Wright, Nikita, et al.
Publicado: (2017)

AURKB-mediated effects on chromatin regulate binding versus release of XIST RNA to the inactive chromosome
por: Hall, Lisa L., et al.
Publicado: (2009)

Multi-omics analysis identifies potential mechanisms of AURKB in mediating poor outcome of lung adenocarcinoma
por: Huang, Jie, et al.
Publicado: (2021)

AURKB, in concert with REST, acts as an oxygen-sensitive epigenetic regulator of the hypoxic induction of MDM2
por: Kim, Iljin, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_nkic55bbg1mqk1tfu37b2s8dji