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Mechanism of cystogenesis by Cd79a-driven, conditional mTOR activation in developing mouse nephrons

Polycystic kidney disease (PKD) is a common genetic disorder arising from developmental and postnatal processes. Defects in primary cilia and their signaling (eg, mTOR) underlie the pathogenesis. However, how mTOR regulates tubular integrity remains unclear. The paucity of faithful models has limite...

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Detalles Bibliográficos
Autores principales:	Tran Nguyen Truc, Linh, Matsuda, Satoshi, Takenouchi, Akiko, Tran Thuy Huong, Quynh, Kotani, Yui, Miyazaki, Tatsuhiko, Kanda, Hiroaki, Yoshizawa, Katsuhiko, Tsukaguchi, Hiroyasu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9832032/ https://www.ncbi.nlm.nih.gov/pubmed/36627370 http://dx.doi.org/10.1038/s41598-023-27766-2

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