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Optimal vaccination: various (counter) intuitive examples
In previous articles, we formalized the problem of optimal allocation strategies for a (perfect) vaccine in an infinite-dimensional metapopulation model. The aim of the current paper is to illustrate this theoretical framework with multiple examples where one can derive the analytic expression of th...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9832132/ https://www.ncbi.nlm.nih.gov/pubmed/36625980 http://dx.doi.org/10.1007/s00285-022-01858-5 |
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author | Delmas, Jean-François Dronnier, Dylan Zitt, Pierre-André |
author_facet | Delmas, Jean-François Dronnier, Dylan Zitt, Pierre-André |
author_sort | Delmas, Jean-François |
collection | PubMed |
description | In previous articles, we formalized the problem of optimal allocation strategies for a (perfect) vaccine in an infinite-dimensional metapopulation model. The aim of the current paper is to illustrate this theoretical framework with multiple examples where one can derive the analytic expression of the optimal strategies. We discuss in particular the following points: whether or not it is possible to vaccinate optimally when the vaccine doses are given one at a time (greedy vaccination strategies); the effect of assortativity (that is, the tendency to have more contacts with similar individuals) on the shape of optimal vaccination strategies; the particular case where everybody has the same number of neighbors. |
format | Online Article Text |
id | pubmed-9832132 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | Springer Berlin Heidelberg |
record_format | MEDLINE/PubMed |
spelling | pubmed-98321322023-01-12 Optimal vaccination: various (counter) intuitive examples Delmas, Jean-François Dronnier, Dylan Zitt, Pierre-André J Math Biol Article In previous articles, we formalized the problem of optimal allocation strategies for a (perfect) vaccine in an infinite-dimensional metapopulation model. The aim of the current paper is to illustrate this theoretical framework with multiple examples where one can derive the analytic expression of the optimal strategies. We discuss in particular the following points: whether or not it is possible to vaccinate optimally when the vaccine doses are given one at a time (greedy vaccination strategies); the effect of assortativity (that is, the tendency to have more contacts with similar individuals) on the shape of optimal vaccination strategies; the particular case where everybody has the same number of neighbors. Springer Berlin Heidelberg 2023-01-10 2023 /pmc/articles/PMC9832132/ /pubmed/36625980 http://dx.doi.org/10.1007/s00285-022-01858-5 Text en © The Author(s) 2023 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . |
spellingShingle | Article Delmas, Jean-François Dronnier, Dylan Zitt, Pierre-André Optimal vaccination: various (counter) intuitive examples |
title | Optimal vaccination: various (counter) intuitive examples |
title_full | Optimal vaccination: various (counter) intuitive examples |
title_fullStr | Optimal vaccination: various (counter) intuitive examples |
title_full_unstemmed | Optimal vaccination: various (counter) intuitive examples |
title_short | Optimal vaccination: various (counter) intuitive examples |
title_sort | optimal vaccination: various (counter) intuitive examples |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9832132/ https://www.ncbi.nlm.nih.gov/pubmed/36625980 http://dx.doi.org/10.1007/s00285-022-01858-5 |
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