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New approaches to epidemic modeling on networks

In this article, we develop two independent and new approaches to model epidemic spread in a network. Contrary to the most studied models, those developed here allow for contacts with different probabilities of transmitting the disease (transmissibilities). We then examine each of these models using...

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Autores principales: Gómez, Arturo, Oliveira, Gonçalo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9832162/
https://www.ncbi.nlm.nih.gov/pubmed/36627299
http://dx.doi.org/10.1038/s41598-022-19827-9
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author Gómez, Arturo
Oliveira, Gonçalo
author_facet Gómez, Arturo
Oliveira, Gonçalo
author_sort Gómez, Arturo
collection PubMed
description In this article, we develop two independent and new approaches to model epidemic spread in a network. Contrary to the most studied models, those developed here allow for contacts with different probabilities of transmitting the disease (transmissibilities). We then examine each of these models using some mean field type approximations. The first model looks at the late-stage effects of an epidemic outbreak and allows for the computation of the probability that a given vertex was infected. This computation is based on a mean field approximation and only depends on the number of contacts and their transmissibilities. This approach shares many similarities with percolation models in networks. The second model we develop is a dynamic model which we analyze using a mean field approximation which highly reduces the dimensionality of the system. In particular, the original system which individually analyses each vertex of the network is reduced to one with as many equations as different transmissibilities. Perhaps the greatest contribution of this article is the observation that, in both these models, the existence and size of an epidemic outbreak are linked to the properties of a matrix which we call the [Formula: see text] -matrix. This is a generalization of the basic reproduction number which more precisely characterizes the main routes of infection.
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spelling pubmed-98321622023-01-12 New approaches to epidemic modeling on networks Gómez, Arturo Oliveira, Gonçalo Sci Rep Article In this article, we develop two independent and new approaches to model epidemic spread in a network. Contrary to the most studied models, those developed here allow for contacts with different probabilities of transmitting the disease (transmissibilities). We then examine each of these models using some mean field type approximations. The first model looks at the late-stage effects of an epidemic outbreak and allows for the computation of the probability that a given vertex was infected. This computation is based on a mean field approximation and only depends on the number of contacts and their transmissibilities. This approach shares many similarities with percolation models in networks. The second model we develop is a dynamic model which we analyze using a mean field approximation which highly reduces the dimensionality of the system. In particular, the original system which individually analyses each vertex of the network is reduced to one with as many equations as different transmissibilities. Perhaps the greatest contribution of this article is the observation that, in both these models, the existence and size of an epidemic outbreak are linked to the properties of a matrix which we call the [Formula: see text] -matrix. This is a generalization of the basic reproduction number which more precisely characterizes the main routes of infection. Nature Publishing Group UK 2023-01-10 /pmc/articles/PMC9832162/ /pubmed/36627299 http://dx.doi.org/10.1038/s41598-022-19827-9 Text en © The Author(s) 2023 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Article
Gómez, Arturo
Oliveira, Gonçalo
New approaches to epidemic modeling on networks
title New approaches to epidemic modeling on networks
title_full New approaches to epidemic modeling on networks
title_fullStr New approaches to epidemic modeling on networks
title_full_unstemmed New approaches to epidemic modeling on networks
title_short New approaches to epidemic modeling on networks
title_sort new approaches to epidemic modeling on networks
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9832162/
https://www.ncbi.nlm.nih.gov/pubmed/36627299
http://dx.doi.org/10.1038/s41598-022-19827-9
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