Cargando…

Doppler parameters of ophthalmic artery in women with preeclampsia: A meta‐analysis

Preeclampsia is a progressive and severe cardiovascular disorder in pregnant women. To determine the potential significance of ophthalmic Doppler parameters in preeclamptic women and to provide evidence‐based hints for clinical practice and scientific investigation. We searched PubMed, Embase, Web o...

Descripción completa

Detalles Bibliográficos
Autores principales: Dai, Xinxin, Kang, Li, Ge, Huiyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9832230/
https://www.ncbi.nlm.nih.gov/pubmed/36495167
http://dx.doi.org/10.1111/jch.14611
_version_ 1784868014470987776
author Dai, Xinxin
Kang, Li
Ge, Huiyu
author_facet Dai, Xinxin
Kang, Li
Ge, Huiyu
author_sort Dai, Xinxin
collection PubMed
description Preeclampsia is a progressive and severe cardiovascular disorder in pregnant women. To determine the potential significance of ophthalmic Doppler parameters in preeclamptic women and to provide evidence‐based hints for clinical practice and scientific investigation. We searched PubMed, Embase, Web of Science, and the Cochrane Library till July 31, 2022. Pooled standardized mean difference (SMD) with 95% confidence intervals (CIs) were calculated using the random effects model. Heterogeneity across included studies was evaluated utilizing the Q test and I (2) statistic. We identified 8 observational studies that met the inclusion criteria. The pooled SMD for peak systolic velocities (PSV) was .12 (95% CI: −.82, 1.06, p = .8071; I (2) = 94%, p < .0001). The overall SMD for time‐averaged mean peak velocities (MV) was 1.79 (95% CI: .87, 2.71, p = .0001; I (2) = 60%, p = .1152). Regarding the pulsatility index (PI), the pooled SMD was −2.05 (95% CI: −3.12, −.98, p = .0002; I (2) = 92%, p < .0001). Overall SMD for end‐diastolic velocities (EDV) was 1.11 (95% CI: .23, 1.98, p = .0136; I (2) = 92%, p < .0001). The pooled SMDs for resistance index (RI) and peak ratio (PR) was −.18 (95% CI: −1.90, 1.53, p = .8333; I (2) = 96%, p < .0001) and 1.46 (95% CI: −1.30, 4.22, p = .2994; I (2) = 99%, p < .0001), respectively. Publication bias was not identified. MV, PI, and EDV showed significant differences between patients with preeclampsia and non‐hypertensive pregnant participants. Studies on the predictive performance of ophthalmic artery Doppler parameters are warranted.
format Online
Article
Text
id pubmed-9832230
institution National Center for Biotechnology Information
language English
publishDate 2022
publisher John Wiley and Sons Inc.
record_format MEDLINE/PubMed
spelling pubmed-98322302023-01-12 Doppler parameters of ophthalmic artery in women with preeclampsia: A meta‐analysis Dai, Xinxin Kang, Li Ge, Huiyu J Clin Hypertens (Greenwich) Meta‐analyses Preeclampsia is a progressive and severe cardiovascular disorder in pregnant women. To determine the potential significance of ophthalmic Doppler parameters in preeclamptic women and to provide evidence‐based hints for clinical practice and scientific investigation. We searched PubMed, Embase, Web of Science, and the Cochrane Library till July 31, 2022. Pooled standardized mean difference (SMD) with 95% confidence intervals (CIs) were calculated using the random effects model. Heterogeneity across included studies was evaluated utilizing the Q test and I (2) statistic. We identified 8 observational studies that met the inclusion criteria. The pooled SMD for peak systolic velocities (PSV) was .12 (95% CI: −.82, 1.06, p = .8071; I (2) = 94%, p < .0001). The overall SMD for time‐averaged mean peak velocities (MV) was 1.79 (95% CI: .87, 2.71, p = .0001; I (2) = 60%, p = .1152). Regarding the pulsatility index (PI), the pooled SMD was −2.05 (95% CI: −3.12, −.98, p = .0002; I (2) = 92%, p < .0001). Overall SMD for end‐diastolic velocities (EDV) was 1.11 (95% CI: .23, 1.98, p = .0136; I (2) = 92%, p < .0001). The pooled SMDs for resistance index (RI) and peak ratio (PR) was −.18 (95% CI: −1.90, 1.53, p = .8333; I (2) = 96%, p < .0001) and 1.46 (95% CI: −1.30, 4.22, p = .2994; I (2) = 99%, p < .0001), respectively. Publication bias was not identified. MV, PI, and EDV showed significant differences between patients with preeclampsia and non‐hypertensive pregnant participants. Studies on the predictive performance of ophthalmic artery Doppler parameters are warranted. John Wiley and Sons Inc. 2022-12-10 /pmc/articles/PMC9832230/ /pubmed/36495167 http://dx.doi.org/10.1111/jch.14611 Text en © 2022 The Authors. The Journal of Clinical Hypertension published by Wiley Periodicals LLC. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ (https://creativecommons.org/licenses/by-nc-nd/4.0/) License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.
spellingShingle Meta‐analyses
Dai, Xinxin
Kang, Li
Ge, Huiyu
Doppler parameters of ophthalmic artery in women with preeclampsia: A meta‐analysis
title Doppler parameters of ophthalmic artery in women with preeclampsia: A meta‐analysis
title_full Doppler parameters of ophthalmic artery in women with preeclampsia: A meta‐analysis
title_fullStr Doppler parameters of ophthalmic artery in women with preeclampsia: A meta‐analysis
title_full_unstemmed Doppler parameters of ophthalmic artery in women with preeclampsia: A meta‐analysis
title_short Doppler parameters of ophthalmic artery in women with preeclampsia: A meta‐analysis
title_sort doppler parameters of ophthalmic artery in women with preeclampsia: a meta‐analysis
topic Meta‐analyses
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9832230/
https://www.ncbi.nlm.nih.gov/pubmed/36495167
http://dx.doi.org/10.1111/jch.14611
work_keys_str_mv AT daixinxin dopplerparametersofophthalmicarteryinwomenwithpreeclampsiaametaanalysis
AT kangli dopplerparametersofophthalmicarteryinwomenwithpreeclampsiaametaanalysis
AT gehuiyu dopplerparametersofophthalmicarteryinwomenwithpreeclampsiaametaanalysis