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Doppler parameters of ophthalmic artery in women with preeclampsia: A meta‐analysis
Preeclampsia is a progressive and severe cardiovascular disorder in pregnant women. To determine the potential significance of ophthalmic Doppler parameters in preeclamptic women and to provide evidence‐based hints for clinical practice and scientific investigation. We searched PubMed, Embase, Web o...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9832230/ https://www.ncbi.nlm.nih.gov/pubmed/36495167 http://dx.doi.org/10.1111/jch.14611 |
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author | Dai, Xinxin Kang, Li Ge, Huiyu |
author_facet | Dai, Xinxin Kang, Li Ge, Huiyu |
author_sort | Dai, Xinxin |
collection | PubMed |
description | Preeclampsia is a progressive and severe cardiovascular disorder in pregnant women. To determine the potential significance of ophthalmic Doppler parameters in preeclamptic women and to provide evidence‐based hints for clinical practice and scientific investigation. We searched PubMed, Embase, Web of Science, and the Cochrane Library till July 31, 2022. Pooled standardized mean difference (SMD) with 95% confidence intervals (CIs) were calculated using the random effects model. Heterogeneity across included studies was evaluated utilizing the Q test and I (2) statistic. We identified 8 observational studies that met the inclusion criteria. The pooled SMD for peak systolic velocities (PSV) was .12 (95% CI: −.82, 1.06, p = .8071; I (2) = 94%, p < .0001). The overall SMD for time‐averaged mean peak velocities (MV) was 1.79 (95% CI: .87, 2.71, p = .0001; I (2) = 60%, p = .1152). Regarding the pulsatility index (PI), the pooled SMD was −2.05 (95% CI: −3.12, −.98, p = .0002; I (2) = 92%, p < .0001). Overall SMD for end‐diastolic velocities (EDV) was 1.11 (95% CI: .23, 1.98, p = .0136; I (2) = 92%, p < .0001). The pooled SMDs for resistance index (RI) and peak ratio (PR) was −.18 (95% CI: −1.90, 1.53, p = .8333; I (2) = 96%, p < .0001) and 1.46 (95% CI: −1.30, 4.22, p = .2994; I (2) = 99%, p < .0001), respectively. Publication bias was not identified. MV, PI, and EDV showed significant differences between patients with preeclampsia and non‐hypertensive pregnant participants. Studies on the predictive performance of ophthalmic artery Doppler parameters are warranted. |
format | Online Article Text |
id | pubmed-9832230 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | John Wiley and Sons Inc. |
record_format | MEDLINE/PubMed |
spelling | pubmed-98322302023-01-12 Doppler parameters of ophthalmic artery in women with preeclampsia: A meta‐analysis Dai, Xinxin Kang, Li Ge, Huiyu J Clin Hypertens (Greenwich) Meta‐analyses Preeclampsia is a progressive and severe cardiovascular disorder in pregnant women. To determine the potential significance of ophthalmic Doppler parameters in preeclamptic women and to provide evidence‐based hints for clinical practice and scientific investigation. We searched PubMed, Embase, Web of Science, and the Cochrane Library till July 31, 2022. Pooled standardized mean difference (SMD) with 95% confidence intervals (CIs) were calculated using the random effects model. Heterogeneity across included studies was evaluated utilizing the Q test and I (2) statistic. We identified 8 observational studies that met the inclusion criteria. The pooled SMD for peak systolic velocities (PSV) was .12 (95% CI: −.82, 1.06, p = .8071; I (2) = 94%, p < .0001). The overall SMD for time‐averaged mean peak velocities (MV) was 1.79 (95% CI: .87, 2.71, p = .0001; I (2) = 60%, p = .1152). Regarding the pulsatility index (PI), the pooled SMD was −2.05 (95% CI: −3.12, −.98, p = .0002; I (2) = 92%, p < .0001). Overall SMD for end‐diastolic velocities (EDV) was 1.11 (95% CI: .23, 1.98, p = .0136; I (2) = 92%, p < .0001). The pooled SMDs for resistance index (RI) and peak ratio (PR) was −.18 (95% CI: −1.90, 1.53, p = .8333; I (2) = 96%, p < .0001) and 1.46 (95% CI: −1.30, 4.22, p = .2994; I (2) = 99%, p < .0001), respectively. Publication bias was not identified. MV, PI, and EDV showed significant differences between patients with preeclampsia and non‐hypertensive pregnant participants. Studies on the predictive performance of ophthalmic artery Doppler parameters are warranted. John Wiley and Sons Inc. 2022-12-10 /pmc/articles/PMC9832230/ /pubmed/36495167 http://dx.doi.org/10.1111/jch.14611 Text en © 2022 The Authors. The Journal of Clinical Hypertension published by Wiley Periodicals LLC. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ (https://creativecommons.org/licenses/by-nc-nd/4.0/) License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made. |
spellingShingle | Meta‐analyses Dai, Xinxin Kang, Li Ge, Huiyu Doppler parameters of ophthalmic artery in women with preeclampsia: A meta‐analysis |
title | Doppler parameters of ophthalmic artery in women with preeclampsia: A meta‐analysis |
title_full | Doppler parameters of ophthalmic artery in women with preeclampsia: A meta‐analysis |
title_fullStr | Doppler parameters of ophthalmic artery in women with preeclampsia: A meta‐analysis |
title_full_unstemmed | Doppler parameters of ophthalmic artery in women with preeclampsia: A meta‐analysis |
title_short | Doppler parameters of ophthalmic artery in women with preeclampsia: A meta‐analysis |
title_sort | doppler parameters of ophthalmic artery in women with preeclampsia: a meta‐analysis |
topic | Meta‐analyses |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9832230/ https://www.ncbi.nlm.nih.gov/pubmed/36495167 http://dx.doi.org/10.1111/jch.14611 |
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