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Inhibition of the TRIM24 bromodomain reactivates latent HIV-1
Expression of the HIV-1 genome by RNA Polymerase II is regulated at multiple steps, as are most cellular genes, including recruitment of general transcription factors and control of transcriptional elongation from the core promoter. We recently discovered that tripartite motif protein TRIM24 is recr...
Autores principales: | Horvath, Riley M., Brumme, Zabrina L., Sadowski, Ivan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9832417/ https://www.ncbi.nlm.nih.gov/pubmed/36631514 http://dx.doi.org/10.1038/s41598-023-27765-3 |
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