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Targeted zinc-finger repressors to the oncogenic HBZ gene inhibit adult T-cell leukemia (ATL) proliferation

Human T-lymphotropic virus type I (HTLV-I) infects CD4+ T-cells resulting in a latent, life-long infection in patients. Crosstalk between oncogenic viral factors results in the transformation of the host cell into an aggressive cancer, adult T-cell leukemia/lymphoma (ATL). ATL has a poor prognosis w...

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Detalles Bibliográficos
Autores principales:	Scott, Tristan A, Soemardy, Citradewi, Ray, Roslyn M, Morris, Kevin V
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2023
Materias:	Nucleic Acid-Based Cancer Therapeutics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9832686/ https://www.ncbi.nlm.nih.gov/pubmed/36644398 http://dx.doi.org/10.1093/narcan/zcac046

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