Cargando…

Elevated neurofilament light chain CSF/serum ratio indicates impaired CSF outflow in idiopathic intracranial hypertension

BACKGROUND: Impaired cerebrospinal fluid (CSF) homeostasis is central to the pathogenesis of idiopathic intracranial hypertension (IIH), although the precise mechanisms involved are still not completely understood. The aim of the current study was to assess the CSF/serum ratio of neurofilament light...

Descripción completa

Detalles Bibliográficos
Autores principales:	Engel, Sinah, Halcour, Johannes, Ellwardt, Erik, Uphaus, Timo, Steffen, Falk, Zipp, Frauke, Bittner, Stefan, Luessi, Felix
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2023
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9832777/ https://www.ncbi.nlm.nih.gov/pubmed/36631830 http://dx.doi.org/10.1186/s12987-022-00403-2

Ejemplares similares

Association of intrathecal pleocytosis and IgG synthesis with axonal damage in early MS
por: Engel, Sinah, et al.
Publicado: (2020)

Implications of extreme serum neurofilament light chain levels for the management of patients with relapsing multiple sclerosis
por: Engel, Sinah, et al.
Publicado: (2021)

Association of serum neurofilament light chain levels and neuropsychiatric manifestations in systemic lupus erythematosus
por: Engel, Sinah, et al.
Publicado: (2021)

Serum Neurofilament Identifies Patients With Multiple Sclerosis With Severe Focal Axonal Damage in a 6-Year Longitudinal Cohort
por: Steffen, Falk, et al.
Publicado: (2022)

Spatial transcriptomics and neurofilament light chain reveal changes in lesion patterns in murine autoimmune neuroinflammation
por: Brummer, Tobias, et al.
Publicado: (2023)

GFAPα IgG-associated encephalitis upon daclizumab treatment of MS
por: Luessi, Felix, et al.
Publicado: (2018)

Impact of Dietary Intervention on Serum Neurofilament Light Chain in Multiple Sclerosis
por: Bock, Markus, et al.
Publicado: (2021)

A Case of Progressive Multifocal Leukoencephalopathy in a Fumaric Acid-Treated Psoriasis Patient With Severe Lymphopenia Among Other Risk Factors
por: Engel, Sinah, et al.
Publicado: (2021)

NfL predicts relapse-free progression in a longitudinal multiple sclerosis cohort study: Serum NfL predicts relapse-free progression
por: Uphaus, Timo, et al.
Publicado: (2021)

Intrathecal B-cell accumulation and axonal damage distinguish MRI-based benign from aggressive onset in MS
por: Engel, Sinah, et al.
Publicado: (2019)

Supplementary medication in multiple sclerosis: Real-world experience and potential interference with neurofilament light chain measurement
por: Pape, Katrin, et al.
Publicado: (2020)

Serum neurofilament levels reflect outer retinal layer changes in multiple sclerosis
por: Seitz, Caspar B., et al.
Publicado: (2021)

MOG encephalomyelitis: distinct clinical, MRI and CSF features in patients with longitudinal extensive transverse myelitis as first clinical presentation
por: Loos, Julia, et al.
Publicado: (2020)

PPMS onset upon adalimumab treatment extends the spectrum of anti-TNF-α therapy-associated demyelinating disorders
por: Engel, Sinah, et al.
Publicado: (2020)

CSF Neurofilament Light Chain Elevation Predicts ALS Severity and Progression
por: Sun, Qionghua, et al.
Publicado: (2020)

Is CSF neurofilament light chain measurement relevant for MS?
por: Matsui, Makoto
Publicado: (2020)

Idiopathic intracranial hypertension presenting as CSF rhinorrhea
por: Saifudheen, K., et al.
Publicado: (2010)

Monitoring B-cell repopulation after depletion therapy in neurologic patients
por: Ellwardt, Erik, et al.
Publicado: (2018)

CSF Neurofilament Light Chain Levels in Primary Progressive MS: Signs of Axonal Neurodegeneration
por: Pawlitzki, Marc, et al.
Publicado: (2018)

CSF-Progranulin and Neurofilament Light Chain Levels in Patients With Radiologically Isolated Syndrome—Sign of Inflammation
por: Pawlitzki, Marc, et al.
Publicado: (2018)

Elevated CSF outflow resistance associated with impaired lymphatic CSF absorption in a rat model of kaolin-induced communicating hydrocephalus
por: Nagra, Gurjit, et al.
Publicado: (2010)

Intracranial pressure elevation alters CSF clearance pathways
por: Vinje, Vegard, et al.
Publicado: (2020)

Preventing disease progression in multiple sclerosis—insights from large real-world cohorts
por: Engel, Sinah, et al.
Publicado: (2022)

CSF neurofilament light chain reflects corticospinal tract degeneration in ALS
por: Menke, Ricarda A L, et al.
Publicado: (2015)

CSF Neurofilament Light Chain Concentrations Predict Outcome in Bacterial Meningitis
por: Chekrouni, Nora, et al.
Publicado: (2021)

The effect of CSF drain on the optic nerve in idiopathic intracranial hypertension
por: Hoffmann, Jan, et al.
Publicado: (2019)

Attenuation of immune activation in patients with multiple sclerosis on a wheat-reduced diet: a pilot crossover trial
por: Engel, Sinah, et al.
Publicado: (2023)

Neurofilaments in blood and CSF for diagnosis and prediction of onset in Creutzfeldt-Jakob disease
por: Steinacker, Petra, et al.
Publicado: (2016)

The potential of serum neurofilament as biomarker for multiple sclerosis
por: Bittner, Stefan, et al.
Publicado: (2021)

Fingolimod and CSF neurofilament light chain levels in relapsing-remitting multiple sclerosis
por: Kuhle, Jens, et al.
Publicado: (2015)

CSF Neurofilament Light Chain but not FLT3 Ligand Discriminates Parkinsonian Disorders
por: Herbert, Megan K., et al.
Publicado: (2015)

CSF Neurofilament light chain level predicts axonal damage in cerebral vasculitis
por: Pawlitzki, Marc, et al.
Publicado: (2019)

CSF neurofilament light chain testing as an aid to determine treatment strategies in MS
por: Reyes, Saúl, et al.
Publicado: (2020)

Neurosurgical CSF Diversion in Idiopathic Intracranial Hypertension: A Narrative Review
por: Sunderland, Geraint J., et al.
Publicado: (2021)

Predictors for insufficient SARS-CoV-2 vaccination response upon treatment in multiple sclerosis
por: Schraad, Muriel, et al.
Publicado: (2022)

Network alterations underlying anxiety symptoms in early multiple sclerosis
por: Ellwardt, Erik, et al.
Publicado: (2022)

The CSF neurofilament light signature in rapidly progressive neurodegenerative dementias
por: Abu-Rumeileh, Samir, et al.
Publicado: (2018)

Improved prediction of early cognitive impairment in multiple sclerosis combining blood and imaging biomarkers
por: Brummer, Tobias, et al.
Publicado: (2022)

Chitinase 3–like 1 and neurofilament light chain in CSF and CNS atrophy in MS
por: Schneider, Ruth, et al.
Publicado: (2020)

High anti-JCPyV serum titers coincide with high CSF cell counts in RRMS patients
por: Schneider-Hohendorf, Tilman, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_gm7t07tm26dvkrsqofaek7la4k