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Interaction of anxiety and hypertension on quality of life among patients with gynecological cancer: a cross-sectional study
BACKGROUND: Patients with gynecological cancer are prone to anxiety, and many of them are accompanied by hypertension, which seriously affects the quality of life (QOL). The study was to explore the interaction of anxiety and hypertension on QOL, and the moderating effect of perceived social support...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9832796/ https://www.ncbi.nlm.nih.gov/pubmed/36631792 http://dx.doi.org/10.1186/s12888-023-04521-5 |
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author | Gu, ZhiHui Yang, ChenXin Tang, Lin Wu, Hui |
author_facet | Gu, ZhiHui Yang, ChenXin Tang, Lin Wu, Hui |
author_sort | Gu, ZhiHui |
collection | PubMed |
description | BACKGROUND: Patients with gynecological cancer are prone to anxiety, and many of them are accompanied by hypertension, which seriously affects the quality of life (QOL). The study was to explore the interaction of anxiety and hypertension on QOL, and the moderating effect of perceived social support (PSS) in the impact of anxiety and hypertension on QOL of patients with gynecological cancer. METHODS: A cross-sectional study was conducted in 2020, and 566 patients have been collected from the Affiliated Hospital of China Medical University. The Self-Rating Anxiety Scale (SAS), the Functional Assessment of Cancer Therapy Genera tool (FACT-G), and the Multidimensional Scale of Perceived Social Support Scale (MSPSS) were used. The interaction was analyzed by additive model, and the moderating effect was conducted by regression analysis and the simple slope analysis. RESULTS: We found that 68.8% of patients had poor QOL due to the interaction between anxiety and hypertension. The relative excess risk ratio (RERI) was 22.238 (95%CI:44.119–88.596); the attribution ratio (AP) was 0.688 (95%CI:0.234–1.142); The interaction index (S) was 3.466 (95%CI: 0.823–14.435). The interaction items of PSS and anxiety were negatively correlated with QOL (β = -0.219, P < 0.01) and explained an additional 4.0% variance (F = 68.649, Adjusted R(2) = 0.399, ΔR(2) = 0.040, P < 0.01); PSS and blood pressure interaction item was not associated with QOL (β = 0.013, F = 55.138, Adjusted R(2) = 0.365, ΔR(2) = 0.001, P = 0.730). CONCLUSIONS: When anxiety and hypertension coexist, the QOL was affected. PSS played a moderating role in the impact of anxiety on QOL. Healthcare providers should take intervention measures to improve patients’ social support to reduce the impact of anxiety on QOL. |
format | Online Article Text |
id | pubmed-9832796 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-98327962023-01-12 Interaction of anxiety and hypertension on quality of life among patients with gynecological cancer: a cross-sectional study Gu, ZhiHui Yang, ChenXin Tang, Lin Wu, Hui BMC Psychiatry Research BACKGROUND: Patients with gynecological cancer are prone to anxiety, and many of them are accompanied by hypertension, which seriously affects the quality of life (QOL). The study was to explore the interaction of anxiety and hypertension on QOL, and the moderating effect of perceived social support (PSS) in the impact of anxiety and hypertension on QOL of patients with gynecological cancer. METHODS: A cross-sectional study was conducted in 2020, and 566 patients have been collected from the Affiliated Hospital of China Medical University. The Self-Rating Anxiety Scale (SAS), the Functional Assessment of Cancer Therapy Genera tool (FACT-G), and the Multidimensional Scale of Perceived Social Support Scale (MSPSS) were used. The interaction was analyzed by additive model, and the moderating effect was conducted by regression analysis and the simple slope analysis. RESULTS: We found that 68.8% of patients had poor QOL due to the interaction between anxiety and hypertension. The relative excess risk ratio (RERI) was 22.238 (95%CI:44.119–88.596); the attribution ratio (AP) was 0.688 (95%CI:0.234–1.142); The interaction index (S) was 3.466 (95%CI: 0.823–14.435). The interaction items of PSS and anxiety were negatively correlated with QOL (β = -0.219, P < 0.01) and explained an additional 4.0% variance (F = 68.649, Adjusted R(2) = 0.399, ΔR(2) = 0.040, P < 0.01); PSS and blood pressure interaction item was not associated with QOL (β = 0.013, F = 55.138, Adjusted R(2) = 0.365, ΔR(2) = 0.001, P = 0.730). CONCLUSIONS: When anxiety and hypertension coexist, the QOL was affected. PSS played a moderating role in the impact of anxiety on QOL. Healthcare providers should take intervention measures to improve patients’ social support to reduce the impact of anxiety on QOL. BioMed Central 2023-01-11 /pmc/articles/PMC9832796/ /pubmed/36631792 http://dx.doi.org/10.1186/s12888-023-04521-5 Text en © The Author(s) 2023 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated in a credit line to the data. |
spellingShingle | Research Gu, ZhiHui Yang, ChenXin Tang, Lin Wu, Hui Interaction of anxiety and hypertension on quality of life among patients with gynecological cancer: a cross-sectional study |
title | Interaction of anxiety and hypertension on quality of life among patients with gynecological cancer: a cross-sectional study |
title_full | Interaction of anxiety and hypertension on quality of life among patients with gynecological cancer: a cross-sectional study |
title_fullStr | Interaction of anxiety and hypertension on quality of life among patients with gynecological cancer: a cross-sectional study |
title_full_unstemmed | Interaction of anxiety and hypertension on quality of life among patients with gynecological cancer: a cross-sectional study |
title_short | Interaction of anxiety and hypertension on quality of life among patients with gynecological cancer: a cross-sectional study |
title_sort | interaction of anxiety and hypertension on quality of life among patients with gynecological cancer: a cross-sectional study |
topic | Research |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9832796/ https://www.ncbi.nlm.nih.gov/pubmed/36631792 http://dx.doi.org/10.1186/s12888-023-04521-5 |
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