Cargando…

Interaction of anxiety and hypertension on quality of life among patients with gynecological cancer: a cross-sectional study

BACKGROUND: Patients with gynecological cancer are prone to anxiety, and many of them are accompanied by hypertension, which seriously affects the quality of life (QOL). The study was to explore the interaction of anxiety and hypertension on QOL, and the moderating effect of perceived social support...

Descripción completa

Detalles Bibliográficos
Autores principales: Gu, ZhiHui, Yang, ChenXin, Tang, Lin, Wu, Hui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9832796/
https://www.ncbi.nlm.nih.gov/pubmed/36631792
http://dx.doi.org/10.1186/s12888-023-04521-5
_version_ 1784868127947882496
author Gu, ZhiHui
Yang, ChenXin
Tang, Lin
Wu, Hui
author_facet Gu, ZhiHui
Yang, ChenXin
Tang, Lin
Wu, Hui
author_sort Gu, ZhiHui
collection PubMed
description BACKGROUND: Patients with gynecological cancer are prone to anxiety, and many of them are accompanied by hypertension, which seriously affects the quality of life (QOL). The study was to explore the interaction of anxiety and hypertension on QOL, and the moderating effect of perceived social support (PSS) in the impact of anxiety and hypertension on QOL of patients with gynecological cancer. METHODS: A cross-sectional study was conducted in 2020, and 566 patients have been collected from the Affiliated Hospital of China Medical University. The Self-Rating Anxiety Scale (SAS), the Functional Assessment of Cancer Therapy Genera tool (FACT-G), and the Multidimensional Scale of Perceived Social Support Scale (MSPSS) were used. The interaction was analyzed by additive model, and the moderating effect was conducted by regression analysis and the simple slope analysis. RESULTS: We found that 68.8% of patients had poor QOL due to the interaction between anxiety and hypertension. The relative excess risk ratio (RERI) was 22.238 (95%CI:44.119–88.596); the attribution ratio (AP) was 0.688 (95%CI:0.234–1.142); The interaction index (S) was 3.466 (95%CI: 0.823–14.435). The interaction items of PSS and anxiety were negatively correlated with QOL (β = -0.219, P < 0.01) and explained an additional 4.0% variance (F = 68.649, Adjusted R(2) = 0.399, ΔR(2) = 0.040, P < 0.01); PSS and blood pressure interaction item was not associated with QOL (β = 0.013, F = 55.138, Adjusted R(2) = 0.365, ΔR(2) = 0.001, P = 0.730). CONCLUSIONS: When anxiety and hypertension coexist, the QOL was affected. PSS played a moderating role in the impact of anxiety on QOL. Healthcare providers should take intervention measures to improve patients’ social support to reduce the impact of anxiety on QOL.
format Online
Article
Text
id pubmed-9832796
institution National Center for Biotechnology Information
language English
publishDate 2023
publisher BioMed Central
record_format MEDLINE/PubMed
spelling pubmed-98327962023-01-12 Interaction of anxiety and hypertension on quality of life among patients with gynecological cancer: a cross-sectional study Gu, ZhiHui Yang, ChenXin Tang, Lin Wu, Hui BMC Psychiatry Research BACKGROUND: Patients with gynecological cancer are prone to anxiety, and many of them are accompanied by hypertension, which seriously affects the quality of life (QOL). The study was to explore the interaction of anxiety and hypertension on QOL, and the moderating effect of perceived social support (PSS) in the impact of anxiety and hypertension on QOL of patients with gynecological cancer. METHODS: A cross-sectional study was conducted in 2020, and 566 patients have been collected from the Affiliated Hospital of China Medical University. The Self-Rating Anxiety Scale (SAS), the Functional Assessment of Cancer Therapy Genera tool (FACT-G), and the Multidimensional Scale of Perceived Social Support Scale (MSPSS) were used. The interaction was analyzed by additive model, and the moderating effect was conducted by regression analysis and the simple slope analysis. RESULTS: We found that 68.8% of patients had poor QOL due to the interaction between anxiety and hypertension. The relative excess risk ratio (RERI) was 22.238 (95%CI:44.119–88.596); the attribution ratio (AP) was 0.688 (95%CI:0.234–1.142); The interaction index (S) was 3.466 (95%CI: 0.823–14.435). The interaction items of PSS and anxiety were negatively correlated with QOL (β = -0.219, P < 0.01) and explained an additional 4.0% variance (F = 68.649, Adjusted R(2) = 0.399, ΔR(2) = 0.040, P < 0.01); PSS and blood pressure interaction item was not associated with QOL (β = 0.013, F = 55.138, Adjusted R(2) = 0.365, ΔR(2) = 0.001, P = 0.730). CONCLUSIONS: When anxiety and hypertension coexist, the QOL was affected. PSS played a moderating role in the impact of anxiety on QOL. Healthcare providers should take intervention measures to improve patients’ social support to reduce the impact of anxiety on QOL. BioMed Central 2023-01-11 /pmc/articles/PMC9832796/ /pubmed/36631792 http://dx.doi.org/10.1186/s12888-023-04521-5 Text en © The Author(s) 2023 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Research
Gu, ZhiHui
Yang, ChenXin
Tang, Lin
Wu, Hui
Interaction of anxiety and hypertension on quality of life among patients with gynecological cancer: a cross-sectional study
title Interaction of anxiety and hypertension on quality of life among patients with gynecological cancer: a cross-sectional study
title_full Interaction of anxiety and hypertension on quality of life among patients with gynecological cancer: a cross-sectional study
title_fullStr Interaction of anxiety and hypertension on quality of life among patients with gynecological cancer: a cross-sectional study
title_full_unstemmed Interaction of anxiety and hypertension on quality of life among patients with gynecological cancer: a cross-sectional study
title_short Interaction of anxiety and hypertension on quality of life among patients with gynecological cancer: a cross-sectional study
title_sort interaction of anxiety and hypertension on quality of life among patients with gynecological cancer: a cross-sectional study
topic Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9832796/
https://www.ncbi.nlm.nih.gov/pubmed/36631792
http://dx.doi.org/10.1186/s12888-023-04521-5
work_keys_str_mv AT guzhihui interactionofanxietyandhypertensiononqualityoflifeamongpatientswithgynecologicalcanceracrosssectionalstudy
AT yangchenxin interactionofanxietyandhypertensiononqualityoflifeamongpatientswithgynecologicalcanceracrosssectionalstudy
AT tanglin interactionofanxietyandhypertensiononqualityoflifeamongpatientswithgynecologicalcanceracrosssectionalstudy
AT wuhui interactionofanxietyandhypertensiononqualityoflifeamongpatientswithgynecologicalcanceracrosssectionalstudy