Cargando…

Depressive patient‐derived GABA interneurons reveal abnormal neural activity associated with HTR2C

Major depressive disorder with suicide behavior (sMDD) is a server mood disorder, bringing tremendous burden to family and society. Although reduced gamma amino butyric acid (GABA) level has been observed in postmortem tissues of sMDD patients, the molecular mechanism by which GABA levels are altere...

Descripción completa

Detalles Bibliográficos
Autores principales:	Lu, Kaiqin, Hong, Yuan, Tao, Mengdan, Shen, Luping, Zheng, Zhilong, Fang, Kaiheng, Yuan, Fang, Xu, Min, Wang, Chun, Zhu, Dongya, Guo, Xing, Liu, Yan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2022
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9832822/ https://www.ncbi.nlm.nih.gov/pubmed/36373384 http://dx.doi.org/10.15252/emmm.202216364

Ejemplares similares

Identification of small molecules for accelerating the differentiation of GABA interneurons from human pluripotent stem cells
por: Shen, Luping, et al.
Publicado: (2020)

Inhibition of GABA interneurons in the mPFC is sufficient and necessary for rapid antidepressant responses
por: Fogaça, Manoela V., et al.
Publicado: (2020)

5-HTR1A and 5-HTR2A genetic polymorphisms and SSRI antidepressant response in depressive Chinese patients
por: Dong, Zai-Quan, et al.
Publicado: (2016)

Tonic excitation or inhibition is set by GABA(A) conductance in hippocampal interneurons
por: Song, Inseon, et al.
Publicado: (2011)

GABA through the Ages: Regulation of Cortical Function and Plasticity by Inhibitory Interneurons
por: Lehmann, Konrad, et al.
Publicado: (2012)

A GABA Interneuron Deficit Model of the Art of Vincent van Gogh
por: Turkheimer, Federico E., et al.
Publicado: (2020)

HTR1A, HTR1B, HTR2A, HTR2C and HTR6 Gene Polymorphisms and Extrapyramidal Side Effects in Haloperidol-Treated Patients with Schizophrenia
por: Grubor, Mirko, et al.
Publicado: (2020)

GABA A receptor π subunit promotes apoptosis of HTR-8/SVneo trophoblastic cells: Implications in preeclampsia
por: LU, JUNJIE, et al.
Publicado: (2016)

GABA Regulates the Multidirectional Tangential Migration of GABAergic Interneurons in Living Neonatal Mice
por: Inada, Hiroyuki, et al.
Publicado: (2011)

Hilar Somatostatin Interneurons Contribute to Synchronized GABA Activity in an In Vitro Epilepsy Model
por: Grosser, Sabine, et al.
Publicado: (2014)

GABA transmission from mAL interneurons regulates aggression in Drosophila males
por: Sengupta, Saheli, et al.
Publicado: (2022)

Control of contextual memory through interneuronal α5-GABA(A) receptors
por: Zhu, Mengwen, et al.
Publicado: (2023)

5-HTR3 and 5-HTR4 located on the mitochondrial membrane and functionally regulated mitochondrial functions
por: Wang, Qingyi, et al.
Publicado: (2016)

Cross-sectional associations among P3NP, HtrA, Hsp70, Apelin and sarcopenia in Taiwanese population
por: Chen, Yuan-Yuei, et al.
Publicado: (2021)

Correction to: Cross-sectional associations among P3NP, HtrA, Hsp70, Apelin and sarcopenia in Taiwanese population
por: Chen, Yuan-Yuei, et al.
Publicado: (2022)

Interneuron- and GABA(A) receptor-specific inhibitory synaptic plasticity in cerebellar Purkinje cells
por: He, Qionger, et al.
Publicado: (2015)

The fate of interneurons, GABA(A) receptor sub‐types and perineuronal nets in Alzheimer's disease
por: Ali, Afia B., et al.
Publicado: (2022)

Evaluation of association of common variants in HTR1A and HTR5A with schizophrenia and executive function
por: Guan, Fanglin, et al.
Publicado: (2016)

Presynaptic GABA(B) receptors functionally uncouple somatostatin interneurons from the active hippocampal network
por: Booker, Sam A, et al.
Publicado: (2020)

Neonatal Oxidative Stress Impairs Cortical Synapse Formation and GABA Homeostasis in Parvalbumin-Expressing Interneurons
por: Scheuer, Till, et al.
Publicado: (2022)

Impact of Developmental Changes of GABA(A) Receptors on Interneuron-NG2 Glia Transmission in the Hippocampus
por: Patt, Linda, et al.
Publicado: (2023)

GABA(B)R-Dependent Long-Term Depression at Hippocampal Synapses between CB1-Positive Interneurons and CA1 Pyramidal Cells
por: Jappy, Dave, et al.
Publicado: (2016)

Genomic structure and expression of the human serotonin 2A receptor gene (HTR2A) locus: identification of novel HTR2A and antisense (HTR2A-AS1) exons
por: Ruble, Cara L., et al.
Publicado: (2016)

Grafted hPSC-derived GABA-ergic interneurons regulate seizures and specific cognitive function in temporal lobe epilepsy
por: Upadhya, Dinesh, et al.
Publicado: (2022)

The function of bacterial HtrA is evolutionally conserved in mammalian HtrA2/Omi
por: Chung, Hea-Jong, et al.
Publicado: (2020)

Molecular Cloning and Functional Characterization of Three 5-HT Receptor Genes (HTR1B, HTR1E, and HTR1F) in Chickens
por: Sun, Caiyun, et al.
Publicado: (2021)

Desynchronization of Neocortical Networks by Asynchronous Release of GABA at Autaptic and Synaptic Contacts from Fast-Spiking Interneurons
por: Manseau, Frédéric, et al.
Publicado: (2010)

Temporal lobe cortical pathology and inhibitory GABA interneuron cell loss are associated with seizures in multiple sclerosis
por: Nicholas, Richard, et al.
Publicado: (2016)

Slc38a1 Conveys Astroglia-Derived Glutamine into GABAergic Interneurons for Neurotransmitter GABA Synthesis
por: Qureshi, Tayyaba, et al.
Publicado: (2020)

Identification of a molecular locus for normalizing dysregulated GABA release from interneurons in the Fragile X brain
por: Yang, Yi-Mei, et al.
Publicado: (2018)

Association of Polymorphisms within the Serotonin Receptor Genes 5-HTR1A, 5-HTR1B, 5-HTR2A and 5-HTR2C and Migraine Susceptibility in a Turkish Population
por: Yücel, Yavuz, et al.
Publicado: (2016)

Polymorphisms in the HTR2A and HTR3A Genes Contribute to Pain in TMD Myalgia
por: Louca Jounger, Sofia, et al.
Publicado: (2021)

Study on the Practice of Enterprise Financial Management System under the Epidemic Norm Based on Artificial Neural Network
por: Ji, Kaiheng
Publicado: (2022)

Neuroinflammation-induced parvalbumin interneuron and oscillation deficits might contribute to neurobehavioral abnormities in a two-hit model of depression
por: Liu, Qing-ren, et al.
Publicado: (2023)

LHX6 is essential for the migration of human pluripotent stem cell-derived GABAergic interneurons
por: Yuan, Fang, et al.
Publicado: (2020)

Evaluation of the Serotonergic Genes htr1A, htr1B, htr2A, and slc6A4 in Aggressive Behavior of Golden Retriever Dogs
por: van den Berg, L., et al.
Publicado: (2007)

5-HTR(2A) and 5-HTR(3A) but not 5-HTR(1A) antagonism impairs the cross-modal reactivation of deprived visual cortex in adulthood
por: Lombaert, Nathalie, et al.
Publicado: (2018)

Tonic GABA(A) Receptor-Mediated Currents of Human Cortical GABAergic Interneurons Vary Amongst Cell Types
por: Field, Martin, et al.
Publicado: (2021)

Analogue signaling of somatodendritic synaptic activity to axon enhances GABA release in young cerebellar molecular layer interneurons
por: Trigo, Federico, et al.
Publicado: (2023)

Patterns of genetic variation and the role of selection in HTR1A and HTR1B in macaques (Macaca)
por: Shattuck, Milena R, et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_6a4ehrqv55h92d2uc6stjmb2ud