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Topical SCD-153, a 4-methyl itaconate prodrug, for the treatment of alopecia areata

Alopecia areata is a chronic hair loss disorder that involves autoimmune disruption of hair follicles by CD8(+)  T cells. Most patients present with patchy hair loss on the scalp that improves spontaneously or with topical and intralesional steroids, topical minoxidil, or topical immunotherapy. Howe...

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Detalles Bibliográficos
Autores principales: Tsai, Jerry, Gori, Sadakatali, Alt, Jesse, Tiwari, Sandhya, Iyer, Jitesh, Talwar, Rashmi, Hinsu, Denish, Ahirwar, Kailash, Mohanty, Swayam, Khunt, Chintan, Sutariya, Brijesh, Jani, Kaushal, Venkatasubbaiah, Venkatesha, Patel, Ashok, Meghapara, Jasmin, Joshi, Kaushal, Sahu, Rajanikanta, Rana, Vijay, Nigade, Prashant, Talluri, Ravi S, Murty, Kadiyala V S N, Joshi, Kiritkumar, Ramanathan, Vikram, Li, Ang, Islam, Nasif, Snajdr, Ivan, Majer, Pavel, Rais, Rana, Slusher, Barbara S, Garza, Luis A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9832969/
https://www.ncbi.nlm.nih.gov/pubmed/36712931
http://dx.doi.org/10.1093/pnasnexus/pgac297