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2,3,7,8-Tetrachlorodibenzo-p-dioxin induces multigenerational alterations in the expression of microRNA in the thymus through epigenetic modifications
2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD), a potent AhR ligand, is an environmental contaminant that is known for mediating toxicity across generations. However, whether TCDD can induce multigenerational changes in the expression of microRNAs (miRs) has not been previously studied. In the current s...
Autores principales: | Singh, Narendra P, Yang, Xiaoming, Bam, Marpe, Nagarkatti, Mitzi, Nagarkatti, Prakash |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9833045/ https://www.ncbi.nlm.nih.gov/pubmed/36712935 http://dx.doi.org/10.1093/pnasnexus/pgac290 |
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