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Polygenic risk score for hypercholesterolemia in a Brazilian familial hypercholesterolemia cohort

BACKGROUND AND AIMS: Familial hypercholesterolemia (FH) is a genetic disorder characterized by high levels of LDL-C leading to premature cardiovascular disease (CAD). Only about 40% of individuals with a clinical diagnosis of FH have a causative genetic variant identified, and a proportion of geneti...

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Detalles Bibliográficos
Autores principales:	Lima, Isabella Ramos, Tada, Mauricio Teruo, Oliveira, Theo G.M., Jannes, Cinthia Elim, Bensenor, Isabela, Lotufo, Paulo A., Santos, Raul D., Krieger, Jose E., Pereira, Alexandre C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2022
Materias:	Full Length Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9833269/ https://www.ncbi.nlm.nih.gov/pubmed/36644206 http://dx.doi.org/10.1016/j.athplu.2022.06.002

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