Case report: a fatal case of Aspergillus felis infection in an immunocompetent host

We report a fatal case of Aspergillus felis invasive rhinosinusitis with secondary cerebral abscesses in an immunocompetent host despite aggressive surgical debridement and combination antifungals. Whilst this organism is known to cause fatalities in cats, only a few cases in humans have been docume...

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Autores principales: Parkes-Smith, Jill, Bauer, Michelle J., Bergh, Haakon, Eidan, Anthony, Forde, Brian M., Hilton, John, Kidd, Timothy J., Schmidt, Campbell, Stewart, Adam G., Harris, Patrick N. A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Microbiology Society 2022
Materias:
Case Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9833418/
https://www.ncbi.nlm.nih.gov/pubmed/36644434
http://dx.doi.org/10.1099/acmi.0.000453
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author Parkes-Smith, Jill
Bauer, Michelle J.
Bergh, Haakon
Eidan, Anthony
Forde, Brian M.
Hilton, John
Kidd, Timothy J.
Schmidt, Campbell
Stewart, Adam G.
Harris, Patrick N. A.
author_facet Parkes-Smith, Jill
Bauer, Michelle J.
Bergh, Haakon
Eidan, Anthony
Forde, Brian M.
Hilton, John
Kidd, Timothy J.
Schmidt, Campbell
Stewart, Adam G.
Harris, Patrick N. A.
author_sort Parkes-Smith, Jill
collection PubMed
description We report a fatal case of Aspergillus felis invasive rhinosinusitis with secondary cerebral abscesses in an immunocompetent host despite aggressive surgical debridement and combination antifungals. Whilst this organism is known to cause fatalities in cats, only a few cases in humans have been documented, all of which had significant immunosuppression. This is the first human death due to A. felis described in an immunocompetent host.
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spelling pubmed-98334182023-01-12 Case report: a fatal case of Aspergillus felis infection in an immunocompetent host Parkes-Smith, Jill Bauer, Michelle J. Bergh, Haakon Eidan, Anthony Forde, Brian M. Hilton, John Kidd, Timothy J. Schmidt, Campbell Stewart, Adam G. Harris, Patrick N. A. Access Microbiol Case Reports We report a fatal case of Aspergillus felis invasive rhinosinusitis with secondary cerebral abscesses in an immunocompetent host despite aggressive surgical debridement and combination antifungals. Whilst this organism is known to cause fatalities in cats, only a few cases in humans have been documented, all of which had significant immunosuppression. This is the first human death due to A. felis described in an immunocompetent host. Microbiology Society 2022-11-21 /pmc/articles/PMC9833418/ /pubmed/36644434 http://dx.doi.org/10.1099/acmi.0.000453 Text en © 2022 The Authors https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License. This article was made open access via a Publish and Read agreement between the Microbiology Society and the corresponding author’s institution.
spellingShingle Case Reports
Parkes-Smith, Jill
Bauer, Michelle J.
Bergh, Haakon
Eidan, Anthony
Forde, Brian M.
Hilton, John
Kidd, Timothy J.
Schmidt, Campbell
Stewart, Adam G.
Harris, Patrick N. A.
Case report: a fatal case of Aspergillus felis infection in an immunocompetent host
title Case report: a fatal case of Aspergillus felis infection in an immunocompetent host
title_full Case report: a fatal case of Aspergillus felis infection in an immunocompetent host
title_fullStr Case report: a fatal case of Aspergillus felis infection in an immunocompetent host
title_full_unstemmed Case report: a fatal case of Aspergillus felis infection in an immunocompetent host
title_short Case report: a fatal case of Aspergillus felis infection in an immunocompetent host
title_sort case report: a fatal case of aspergillus felis infection in an immunocompetent host
topic Case Reports
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9833418/
https://www.ncbi.nlm.nih.gov/pubmed/36644434
http://dx.doi.org/10.1099/acmi.0.000453
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