Thioredoxin reductase 1 regulates hepatic inflammation and macrophage activation during acute cholestatic liver injury

Cholestatic liver diseases, including primary sclerosing cholangitis, are characterized by periportal inflammation with progression to hepatic fibrosis and ultimately cirrhosis. We recently reported that the thioredoxin antioxidant response is dysregulated during primary sclerosing cholangitis. The...

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Detalles Bibliográficos
Autores principales: Shearn, Colin T., Anderson, Aimee L., Miller, Colin G., Noyd, Reed C., Devereaux, Michael W., Balasubramaniyan, Nata, Orlicky, David J., Schmidt, Edward E., Sokol, Ronald J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2023
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9833450/
https://www.ncbi.nlm.nih.gov/pubmed/36633484
http://dx.doi.org/10.1097/HC9.0000000000000020

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