Downregulation of COL12A1 and COL13A1 by a selective EP2 receptor agonist, omidenepag, in human trabecular meshwork cells

Omidenepag isopropyl (OMDI) is an intraocular pressure (IOP)-lowering drug used to treat glaucoma. The active form of OMDI, omidenepag (OMD), lowers elevated IOP, the main risk factor for glaucoma, by increasing the aqueous humor outflow; however, a detailed understanding of this mechanism is lackin...

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Detalles Bibliográficos
Autores principales: Kumon, Masashi, Fuwa, Masahiro, Shimazaki, Atsushi, Odani-Kawabata, Noriko, Iwamura, Ryo, Yoneda, Kenji, Kato, Masatomo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9833537/
https://www.ncbi.nlm.nih.gov/pubmed/36630412
http://dx.doi.org/10.1371/journal.pone.0280331

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9833537/
https://www.ncbi.nlm.nih.gov/pubmed/36630412
http://dx.doi.org/10.1371/journal.pone.0280331

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