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A fast lasso-based method for inferring higher-order interactions

Large-scale genotype-phenotype screens provide a wealth of data for identifying molecular alterations associated with a phenotype. Epistatic effects play an important role in such association studies. For example, siRNA perturbation screens can be used to identify combinatorial gene-silencing effect...

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Detalles Bibliográficos
Autores principales:	Elmes, Kieran, Heywood, Astra, Huang, Zhiyi, Gavryushkin, Alex
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9833600/ https://www.ncbi.nlm.nih.gov/pubmed/36580499 http://dx.doi.org/10.1371/journal.pcbi.1010730

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