Cytokinesis machinery promotes cell dissociation from collectively migrating strands in confinement

Cells tune adherens junction dynamics to regulate epithelial integrity in diverse (patho)physiological processes, including cancer metastasis. We hypothesized that the spatially confining architecture of peritumor stroma promotes metastatic cell dissemination by remodeling cell-cell adhesive interac...

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Detalles Bibliográficos
Autores principales: Law, Robert A., Kiepas, Alexander, Desta, Habben E., Perez Ipiña, Emiliano, Parlani, Maria, Lee, Se Jong, Yankaskas, Christopher L., Zhao, Runchen, Mistriotis, Panagiotis, Wang, Nianchao, Gu, Zhizhan, Kalab, Petr, Friedl, Peter, Camley, Brian A., Konstantopoulos, Konstantinos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2023
Materias:
Biomedicine and Life Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9833664/
https://www.ncbi.nlm.nih.gov/pubmed/36630496
http://dx.doi.org/10.1126/sciadv.abq6480

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