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A coordinated transcriptional switching network mediates antigenic variation of human malaria parasites
Malaria parasites avoid immune clearance through their ability to systematically alter antigens exposed on the surface of infected red blood cells. This is accomplished by tightly regulated transcriptional control of individual members of a large, multicopy gene family called var and is the key to b...
Autores principales: | Zhang, Xu, Florini, Francesca, Visone, Joseph E, Lionardi, Irina, Gross, Mackensie R, Patel, Valay, Deitsch, Kirk W |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9833823/ https://www.ncbi.nlm.nih.gov/pubmed/36515978 http://dx.doi.org/10.7554/eLife.83840 |
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