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A coordinated transcriptional switching network mediates antigenic variation of human malaria parasites

Malaria parasites avoid immune clearance through their ability to systematically alter antigens exposed on the surface of infected red blood cells. This is accomplished by tightly regulated transcriptional control of individual members of a large, multicopy gene family called var and is the key to b...

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Detalles Bibliográficos
Autores principales: Zhang, Xu, Florini, Francesca, Visone, Joseph E, Lionardi, Irina, Gross, Mackensie R, Patel, Valay, Deitsch, Kirk W
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9833823/
https://www.ncbi.nlm.nih.gov/pubmed/36515978
http://dx.doi.org/10.7554/eLife.83840

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