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Recruited monocytes/macrophages drive pulmonary neutrophilic inflammation and irreversible lung tissue remodeling in cystic fibrosis

Persistent neutrophil-dominated lung inflammation contributes to lung damage in cystic fibrosis (CF). However, the mechanisms that drive persistent lung neutrophilia and tissue deterioration in CF are not well characterized. Starting from the observation that, in patients with CF, c-c motif chemokin...

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Detalles Bibliográficos
Autores principales: Öz, Hasan H., Cheng, Ee-Chun, Di Pietro, Caterina, Tebaldi, Toma, Biancon, Giulia, Zeiss, Caroline, Zhang, Ping-Xia, Huang, Pamela H., Esquibies, Sofia S., Britto, Clemente J., Schupp, Jonas C, Murray, Thomas S., Halene, Stephanie, Krause, Diane S., Egan, Marie E., Bruscia, Emanuela M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9833830/
https://www.ncbi.nlm.nih.gov/pubmed/36516754
http://dx.doi.org/10.1016/j.celrep.2022.111797