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Recruited monocytes/macrophages drive pulmonary neutrophilic inflammation and irreversible lung tissue remodeling in cystic fibrosis
Persistent neutrophil-dominated lung inflammation contributes to lung damage in cystic fibrosis (CF). However, the mechanisms that drive persistent lung neutrophilia and tissue deterioration in CF are not well characterized. Starting from the observation that, in patients with CF, c-c motif chemokin...
Autores principales: | Öz, Hasan H., Cheng, Ee-Chun, Di Pietro, Caterina, Tebaldi, Toma, Biancon, Giulia, Zeiss, Caroline, Zhang, Ping-Xia, Huang, Pamela H., Esquibies, Sofia S., Britto, Clemente J., Schupp, Jonas C, Murray, Thomas S., Halene, Stephanie, Krause, Diane S., Egan, Marie E., Bruscia, Emanuela M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9833830/ https://www.ncbi.nlm.nih.gov/pubmed/36516754 http://dx.doi.org/10.1016/j.celrep.2022.111797 |
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