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Ginsenoside F1 attenuates pirarubicin-induced cardiotoxicity by modulating Nrf2 and AKT/Bcl-2 signaling pathways
BACKGROUND: Pirarubicin (THP) is an anthracycline antibiotic used to treat various malignancies in humans. The clinical usefulness of THP is unfortunately limited by its dose-related cardiotoxicity. Ginsenoside F1 (GF1) is a metabolite formed when the ginsenosides Re and Rg1 are hydrolyzed. However,...
Autores principales: | Zhang, Yang, Ma, Jiulong, Liu, Shan, Chen, Chen, Li, Qi, Qin, Meng, Ren, Liqun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9834006/ https://www.ncbi.nlm.nih.gov/pubmed/36644383 http://dx.doi.org/10.1016/j.jgr.2022.06.002 |
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