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Inheritance of paternal DNA damage by histone-mediated repair restriction

How paternal exposure to ionizing radiation affects genetic inheritance and disease risk in the offspring has been a long-standing question in radiation biology. In humans, nearly 80% of transmitted mutations arise in the paternal germline(1), but the transgenerational effects of ionizing radiation...

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Detalles Bibliográficos
Autores principales: Wang, Siyao, Meyer, David H., Schumacher, Björn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9834056/
https://www.ncbi.nlm.nih.gov/pubmed/36544019
http://dx.doi.org/10.1038/s41586-022-05544-w