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Topographic Mapping of the Primary Sensory Cortex Using Intraoperative Optical Imaging and Tactile Irritation

The determination of exact tumor boundaries within eloquent brain regions is essential to maximize the extent of resection. Recent studies showed that intraoperative optical imaging (IOI) combined with median nerve stimulation is a helpful tool for visualization of the primary sensory cortex (PSC)....

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Autores principales: Polanski, Witold H., Oelschlägel, Martin, Juratli, Tareq A., Wahl, Hannes, Krukowski, Pawel M., Morgenstern, Ute, Koch, Edmund, Steiner, Gerald, Schackert, Gabriele, Sobottka, Stephan B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9834102/
https://www.ncbi.nlm.nih.gov/pubmed/36446998
http://dx.doi.org/10.1007/s10548-022-00925-w
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author Polanski, Witold H.
Oelschlägel, Martin
Juratli, Tareq A.
Wahl, Hannes
Krukowski, Pawel M.
Morgenstern, Ute
Koch, Edmund
Steiner, Gerald
Schackert, Gabriele
Sobottka, Stephan B.
author_facet Polanski, Witold H.
Oelschlägel, Martin
Juratli, Tareq A.
Wahl, Hannes
Krukowski, Pawel M.
Morgenstern, Ute
Koch, Edmund
Steiner, Gerald
Schackert, Gabriele
Sobottka, Stephan B.
author_sort Polanski, Witold H.
collection PubMed
description The determination of exact tumor boundaries within eloquent brain regions is essential to maximize the extent of resection. Recent studies showed that intraoperative optical imaging (IOI) combined with median nerve stimulation is a helpful tool for visualization of the primary sensory cortex (PSC). In this technical note, we describe a novel approach of using IOI with painless tactile irritation to demonstrate the feasibility of topographic mapping of different body regions within the PSC. In addition, we compared the IOI results with preoperative functional MRI (fMRI) findings. In five patients with tumors located near the PSC who received tumor removal, IOI with tactile irritation of different body parts and fMRI was applied. We showed that tactile irritation of the hand in local and general anesthesia leads to reliable changes of cerebral blood volume during IOI. Hereby, we observed comparable IOI activation maps regarding the median nerve stimulation, fMRI and tactile irritation of the hand. The tactile irritation of different body areas revealed a plausible topographic distribution along the PSC. With this approach, IOI is also suitable for awake surgeries, since the tactile irritation is painless compared with median nerve stimulation and is congruent to fMRI findings. Further studies are ongoing to standardize this method to enable a broad application within the neurosurgical community.
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spelling pubmed-98341022023-01-13 Topographic Mapping of the Primary Sensory Cortex Using Intraoperative Optical Imaging and Tactile Irritation Polanski, Witold H. Oelschlägel, Martin Juratli, Tareq A. Wahl, Hannes Krukowski, Pawel M. Morgenstern, Ute Koch, Edmund Steiner, Gerald Schackert, Gabriele Sobottka, Stephan B. Brain Topogr Short Communication The determination of exact tumor boundaries within eloquent brain regions is essential to maximize the extent of resection. Recent studies showed that intraoperative optical imaging (IOI) combined with median nerve stimulation is a helpful tool for visualization of the primary sensory cortex (PSC). In this technical note, we describe a novel approach of using IOI with painless tactile irritation to demonstrate the feasibility of topographic mapping of different body regions within the PSC. In addition, we compared the IOI results with preoperative functional MRI (fMRI) findings. In five patients with tumors located near the PSC who received tumor removal, IOI with tactile irritation of different body parts and fMRI was applied. We showed that tactile irritation of the hand in local and general anesthesia leads to reliable changes of cerebral blood volume during IOI. Hereby, we observed comparable IOI activation maps regarding the median nerve stimulation, fMRI and tactile irritation of the hand. The tactile irritation of different body areas revealed a plausible topographic distribution along the PSC. With this approach, IOI is also suitable for awake surgeries, since the tactile irritation is painless compared with median nerve stimulation and is congruent to fMRI findings. Further studies are ongoing to standardize this method to enable a broad application within the neurosurgical community. Springer US 2022-11-29 2023 /pmc/articles/PMC9834102/ /pubmed/36446998 http://dx.doi.org/10.1007/s10548-022-00925-w Text en © The Author(s) 2022 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Short Communication
Polanski, Witold H.
Oelschlägel, Martin
Juratli, Tareq A.
Wahl, Hannes
Krukowski, Pawel M.
Morgenstern, Ute
Koch, Edmund
Steiner, Gerald
Schackert, Gabriele
Sobottka, Stephan B.
Topographic Mapping of the Primary Sensory Cortex Using Intraoperative Optical Imaging and Tactile Irritation
title Topographic Mapping of the Primary Sensory Cortex Using Intraoperative Optical Imaging and Tactile Irritation
title_full Topographic Mapping of the Primary Sensory Cortex Using Intraoperative Optical Imaging and Tactile Irritation
title_fullStr Topographic Mapping of the Primary Sensory Cortex Using Intraoperative Optical Imaging and Tactile Irritation
title_full_unstemmed Topographic Mapping of the Primary Sensory Cortex Using Intraoperative Optical Imaging and Tactile Irritation
title_short Topographic Mapping of the Primary Sensory Cortex Using Intraoperative Optical Imaging and Tactile Irritation
title_sort topographic mapping of the primary sensory cortex using intraoperative optical imaging and tactile irritation
topic Short Communication
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9834102/
https://www.ncbi.nlm.nih.gov/pubmed/36446998
http://dx.doi.org/10.1007/s10548-022-00925-w
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