Cargando…

Recurrent sideroblastic anemia during pregnancy

Sideroblastic anemia is a heterogeneous group of disorders typified by the presence of ring sideroblasts in the bone marrow and has congenital and acquired types. Sideroblastic anemia is a rare event in pregnancy. We report a case of a 32‐year‐old female patient, gravida 4 para 3, 27th weeks pregnan...

Descripción completa

Detalles Bibliográficos
Autores principales: Mohamed, Shehab, Ibrahim, Firyal, Alasafar, Mohamad Najib, Alshurafa, Awni, Akiki, Susanna, Soliman, Dina, Kohla, Samah, Amer, Aliaa, Qasim, Hana, Cherif, Honar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9834147/
https://www.ncbi.nlm.nih.gov/pubmed/36644616
http://dx.doi.org/10.1002/ccr3.6814
_version_ 1784868397193887744
author Mohamed, Shehab
Ibrahim, Firyal
Alasafar, Mohamad Najib
Alshurafa, Awni
Akiki, Susanna
Soliman, Dina
Kohla, Samah
Amer, Aliaa
Qasim, Hana
Cherif, Honar
author_facet Mohamed, Shehab
Ibrahim, Firyal
Alasafar, Mohamad Najib
Alshurafa, Awni
Akiki, Susanna
Soliman, Dina
Kohla, Samah
Amer, Aliaa
Qasim, Hana
Cherif, Honar
author_sort Mohamed, Shehab
collection PubMed
description Sideroblastic anemia is a heterogeneous group of disorders typified by the presence of ring sideroblasts in the bone marrow and has congenital and acquired types. Sideroblastic anemia is a rare event in pregnancy. We report a case of a 32‐year‐old female patient, gravida 4 para 3, 27th weeks pregnant, who presented to the emergency department complaining of palpitation and generalized weakness for 2 weeks. She was found to have severe normochromic normocytic anemia, with hemoglobin of 4.2 g/dl, and low reticulocytes count of 13 × 10(3)/μl. She gave a history of recurrent anemia, which had only occurred during pregnancy. Her bone marrow aspirate showed many ring sideroblasts concluding the diagnosis of sideroblastic anemia (SA). Further investigation revealed a significantly low pyridoxine level (vitamin B6) of (8 nmol/L). The Hb level improved with vitamin B6 replacement, without any transfusion support.
format Online
Article
Text
id pubmed-9834147
institution National Center for Biotechnology Information
language English
publishDate 2023
publisher John Wiley and Sons Inc.
record_format MEDLINE/PubMed
spelling pubmed-98341472023-01-13 Recurrent sideroblastic anemia during pregnancy Mohamed, Shehab Ibrahim, Firyal Alasafar, Mohamad Najib Alshurafa, Awni Akiki, Susanna Soliman, Dina Kohla, Samah Amer, Aliaa Qasim, Hana Cherif, Honar Clin Case Rep Case Report Sideroblastic anemia is a heterogeneous group of disorders typified by the presence of ring sideroblasts in the bone marrow and has congenital and acquired types. Sideroblastic anemia is a rare event in pregnancy. We report a case of a 32‐year‐old female patient, gravida 4 para 3, 27th weeks pregnant, who presented to the emergency department complaining of palpitation and generalized weakness for 2 weeks. She was found to have severe normochromic normocytic anemia, with hemoglobin of 4.2 g/dl, and low reticulocytes count of 13 × 10(3)/μl. She gave a history of recurrent anemia, which had only occurred during pregnancy. Her bone marrow aspirate showed many ring sideroblasts concluding the diagnosis of sideroblastic anemia (SA). Further investigation revealed a significantly low pyridoxine level (vitamin B6) of (8 nmol/L). The Hb level improved with vitamin B6 replacement, without any transfusion support. John Wiley and Sons Inc. 2023-01-11 /pmc/articles/PMC9834147/ /pubmed/36644616 http://dx.doi.org/10.1002/ccr3.6814 Text en © 2023 The Authors. Clinical Case Reports published by John Wiley & Sons Ltd. https://creativecommons.org/licenses/by-nc/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc/4.0/ (https://creativecommons.org/licenses/by-nc/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes.
spellingShingle Case Report
Mohamed, Shehab
Ibrahim, Firyal
Alasafar, Mohamad Najib
Alshurafa, Awni
Akiki, Susanna
Soliman, Dina
Kohla, Samah
Amer, Aliaa
Qasim, Hana
Cherif, Honar
Recurrent sideroblastic anemia during pregnancy
title Recurrent sideroblastic anemia during pregnancy
title_full Recurrent sideroblastic anemia during pregnancy
title_fullStr Recurrent sideroblastic anemia during pregnancy
title_full_unstemmed Recurrent sideroblastic anemia during pregnancy
title_short Recurrent sideroblastic anemia during pregnancy
title_sort recurrent sideroblastic anemia during pregnancy
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9834147/
https://www.ncbi.nlm.nih.gov/pubmed/36644616
http://dx.doi.org/10.1002/ccr3.6814
work_keys_str_mv AT mohamedshehab recurrentsideroblasticanemiaduringpregnancy
AT ibrahimfiryal recurrentsideroblasticanemiaduringpregnancy
AT alasafarmohamadnajib recurrentsideroblasticanemiaduringpregnancy
AT alshurafaawni recurrentsideroblasticanemiaduringpregnancy
AT akikisusanna recurrentsideroblasticanemiaduringpregnancy
AT solimandina recurrentsideroblasticanemiaduringpregnancy
AT kohlasamah recurrentsideroblasticanemiaduringpregnancy
AT ameraliaa recurrentsideroblasticanemiaduringpregnancy
AT qasimhana recurrentsideroblasticanemiaduringpregnancy
AT cherifhonar recurrentsideroblasticanemiaduringpregnancy