Cargando…
Two pan-SARS-CoV-2 nanobodies and their multivalent derivatives effectively prevent Omicron infections in mice
With the widespread vaccinations against coronavirus disease 2019 (COVID-19), we are witnessing gradually waning neutralizing antibodies and increasing cases of breakthrough infections, necessitating the development of drugs aside from vaccines, particularly ones that can be administered outside of...
Autores principales: | Liu, Honghui, Wu, Lili, Liu, Bo, Xu, Ke, Lei, Wenwen, Deng, Jianguo, Rong, Xiaoyu, Du, Pei, Wang, Lebing, Wang, Dongbin, Zhang, Xiaolong, Su, Chao, Bi, Yuhai, Chen, Hua, Liu, William J., Qi, Jianxun, Cui, Qingwei, Qi, Shuhui, Fan, Ruiwen, Jiang, Jingkun, Wu, Guizhen, Gao, George F., Wang, Qihui |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9834170/ https://www.ncbi.nlm.nih.gov/pubmed/36702124 http://dx.doi.org/10.1016/j.xcrm.2023.100918 |
Ejemplares similares
-
A broadly neutralizing nanobody targeting the highly conserved S2 subunit of sarbecoviruses
por: Wang, Xiaoyun, et al.
Publicado: (2023) -
A Multivalent and Thermostable Nanobody Neutralizing SARS-CoV-2 Omicron (B.1.1.529)
por: Lu, Yuying, et al.
Publicado: (2023) -
Neutralization of Human Interleukin 23 by Multivalent Nanobodies Explained by the Structure of Cytokine–Nanobody Complex
por: Desmyter, Aline, et al.
Publicado: (2017) -
Versatile and multivalent nanobodies efficiently neutralize SARS-CoV-2
por: Xiang, Yufei, et al.
Publicado: (2020) -
Research Progress and Applications of Multivalent, Multispecific and Modified Nanobodies for Disease Treatment
por: Wang, Jiewen, et al.
Publicado: (2022)