TLR3 forms a laterally aligned multimeric complex along double-stranded RNA for efficient signal transduction

Toll-like receptor 3 (TLR3) is a member of the TLR family, which plays an important role in the innate immune system and is responsible for recognizing viral double-stranded RNA (dsRNA). Previous biochemical and structural studies have revealed that a minimum length of approximately 40–50 base pairs...

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Detalles Bibliográficos
Autores principales: Sakaniwa, Kentaro, Fujimura, Akiko, Shibata, Takuma, Shigematsu, Hideki, Ekimoto, Toru, Yamamoto, Masaki, Ikeguchi, Mitsunori, Miyake, Kensuke, Ohto, Umeharu, Shimizu, Toshiyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9834221/
https://www.ncbi.nlm.nih.gov/pubmed/36631495
http://dx.doi.org/10.1038/s41467-023-35844-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9834221/
https://www.ncbi.nlm.nih.gov/pubmed/36631495
http://dx.doi.org/10.1038/s41467-023-35844-2

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