Allele-specific expression analysis for complex genetic phenotypes applied to a unique dilated cardiomyopathy cohort

Allele-specific expression (ASE) analysis detects the relative abundance of alleles at heterozygous loci as a proxy for cis-regulatory variation, which affects the personal transcriptome and proteome. This study describes the development and application of an ASE analysis pipeline on a unique cohort...

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Detalles Bibliográficos
Autores principales: van Beek, Daan, Verdonschot, Job, Derks, Kasper, Brunner, Han, de Kok, Theo M., Arts, Ilja C. W., Heymans, Stephane, Kutmon, Martina, Adriaens, Michiel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9834222/
https://www.ncbi.nlm.nih.gov/pubmed/36631531
http://dx.doi.org/10.1038/s41598-023-27591-7

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