Cargando…

Porphyromonas gingivalis bacteremia increases the permeability of the blood-brain barrier via the Mfsd2a/Caveolin-1 mediated transcytosis pathway

Bacteremia induced by periodontal infection is an important factor for periodontitis to threaten general health. P. gingivalis DNA/virulence factors have been found in the brain tissues from patients with Alzheimer’s disease (AD). The blood-brain barrier (BBB) is essential for keeping toxic substanc...

Descripción completa

Detalles Bibliográficos
Autores principales: Lei, Shuang, Li, Jian, Yu, Jingjun, Li, Fulong, Pan, Yaping, Chen, Xu, Ma, Chunliang, Zhao, Weidong, Tang, Xiaolin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9834243/
https://www.ncbi.nlm.nih.gov/pubmed/36631446
http://dx.doi.org/10.1038/s41368-022-00215-y