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Simplifying the detection and monitoring of protein glycosylation during in vitro glycoengineering
The majority of mammalian proteins are glycosylated, with the glycans serving to modulate a wide range of biological activities. Variations in protein glycosylation can have dramatic effects on protein stability, immunogenicity, antibody effector function, pharmacological safety and potency, as well...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9834283/ https://www.ncbi.nlm.nih.gov/pubmed/36631484 http://dx.doi.org/10.1038/s41598-023-27634-z |